Results 191 to 200 of about 14,407 (231)

Elastase activity in experimental pancreatitis

Bulletin of Experimental Biology and Medicine, 1980
The activity of elastase, elastase inhibitor and isozymes of lactate dehydrogenase (LDH) was studied in 11 dogs with experimental pancreatitis and 5 control dogs. All dogs with experimental pancreatitis died 6--14 hours after the induction of pancreatitis. Morbid anatomy studies proved severe pancreonecrosis.
V. A. Kubyshkin, I. I. Musin, R. G. Ambartsumyan, L. V. Mikrikova, A. A. Aleksandrov, A. A. Izotova   +5 more
openaire   +1 more source

Purification and characterization of ovine pancreatic elastase

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 1998
Elastase was isolated from ovine pancreas and purified to homogeneity by two different procedures. One involved precipitation with ammonium sulphate, p-aminobenzamidine-Sepharose chromatography, CM-Sepharose ion exchange chromatography and S-300 Sephacryl chromatography.
L S, Erlendsson, H, Filippusson
openaire   +2 more sources

Serum elastase I levels in pancreatic disease

The American Journal of Surgery, 1982
The radioimmunoassay for human elastase I used in this study is accurate, sensitive, and specific, which we have confirmed. The assay can be done within 4 hours, which is important for clinical purposes. A total o 103 subjects were examined, and levels of 99 to 370 ng/dl (mean 200) in normal human sera were determined.
K, Satake, Y S, Chung, K, Umeyama
openaire   +2 more sources

Inhibition of Pancreatic Elastase by Polyphenolic Compounds

Journal of Agricultural and Food Chemistry, 2010
Polyphenols are plant secondary metabolites commonly present in the human diet that possess the ability to bind and inhibit digestive proteins. In the present study, kinetic measurements of porcine pancreatic elastase (PPE) activity were determined using Suc-(Ala)(3)-p-nitroanilide as substrate and polyphenolic compounds as inhibitors.
Natercia F Bras, Rui Goncalves, Nuno Mateus, Pedro A Fernandes, Maria Joao Ramos, Victor Do Freitas   +5 more
openaire   +3 more sources

Fecal Elastase 1 Determination in Chronic Pancreatitis

Digestive Diseases and Sciences, 1999
This study assessed the diagnostic accuracy of fecal elastase 1 in chronic pancreatitis. Fifty-three healthy subjects, 44 patients with chronic pancreatitis (22 severe, 13 moderate, and 9 mild), and 43 patients with nonpancreatic digestive disease were studied.
L, Gullo, M, Ventrucci, P, Tomassetti, M, Migliori, R, Pezzilli   +4 more
openaire   +2 more sources

Elastase 1 in Acute Pancreatitis

1987
Besides the introduction of new imaging techniques, the diagnostics of acute pancreatitis have been improved in the last 10 years by new methods of specific pancreatic enzyme determination in serum [3, 7, 8, 11, 18]. Elastase of the pancreas seems to play a dominant role in the pathogenesis of acute pancreatitis, since this proteolytic and elastolytic ...
M. Büchler, W. Uhl, P. Malfertheiner
openaire   +1 more source

[Pancreatic elastase 1].

Rinsho byori. The Japanese journal of clinical pathology, 2002
Pancreatic elastase 1 is secreted from pancreatic acinar cells as one of the digestive enzymes. Pancreatic elastase 1 is present in serum in a complex formation with alpha 1-antitrypsin, and is measured by immunological methods. Serum pancreatic elastase 1 increases in acute pancreatitis and chronic relapsing pancreatitis.
openaire   +1 more source

Comparison of the Elastolytic Effects of Human Leukocyte Elastase and Porcine Pancreatic Elastase

Biochemical and Biophysical Research Communications, 1976
Porcine and bovine elastins were digested by human leukocyte elastase and porcine pancreatic elastase. The enzymes showed similarities in the extent to which they digested elastin and the pattern and quantitative distribution of N-terminal amino acids in the digests.
R M, Senior, D R, Bielefeld, B C, Starcher   +2 more
openaire   +3 more sources

Isolation and characterization of rat pancreatic elastase

Biochemistry, 1983
Proelastase has been purified to homogeneity from rat pancreatic tissue by a combination of CM-Sephadex and immobilized protease inhibitor affinity resins. Trypsin activation yields an elastolytic enzyme that possesses a specificity toward small hydrophobic residues in synthetic amide substrates, similar to those of porcine elastase 1 and canine ...
openaire   +2 more sources

[Elastase activity in experimental pancreatitis].

Biulleten' eksperimental'noi biologii i meditsiny, 1981
The activity of elastase, elastase inhibitor and isozymes of lactate dehydrogenase (LDH) was studied in 11 dogs with experimental pancreatitis and 5 control dogs. All dogs with experimental pancreatitis died 6--14 hours after the induction of pancreatitis. Morbid anatomy studies proved severe pancreonecrosis.
V A, Kubyshkin, I I, Musin, R G, Ambartsumian, L V, Mikrikova, A A, Aleksandrov   +4 more
openaire   +1 more source