Results 271 to 280 of about 439,784 (298)
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Serum elastase 1 in chronic pancreatic disease

Klinische Wochenschrift, 1985
Elastase 1 and immunoreactive trypsin were assessed by a RIA technique in the sera of 29 control subjects, 24 pancreatic cancer patients, 22 patients with chronic pancreatitis and 31 with extra-pancreatic diseases to ascertain and compare their usefulness in chronic pancreatic disease diagnosis.
DEL FAVERO G.   +7 more
openaire   +3 more sources

[92] Pancreatic elastase

1962
Publisher Summary As the mechanism of action of elastase is not definitely known, all assay methods are based on measuring the amount of insoluble substrate solubilized in a certain time. The assay described can be used with crude preparations, as other pancreatic enzymes do not attack elastin.
openaire   +2 more sources

Determination of immunoreactive trypsin, pancreatic elastase and chymotrypsin in extracts of human feces and ileostomy drainage.

Digestion, 1983
The total daily amount of extractable cationic trypsin, chymotrypsin, and pancreatic elastase 2 in feces and ileostomy fluids has been studied in normal individuals and healthy colectomized subjects.
M. Bohe   +3 more
semanticscholar   +1 more source

Serum human pancreatic elastase I levels in pancreatic disease

Clinica Chimica Acta, 1987
The serum elastase concentration has been measured in 25 healthy individuals, sixteen patients with tumours involving the pancreas, nine patients with acute pancreatitis and nine patients with chronic pancreatitis. The elastase concentrations were increased in those with pancreatic tumours particularly when the head of the pancreas was involved.
Andrew W. Skillen   +3 more
openaire   +3 more sources

Inhibition of human leukocyte and porcine pancreatic elastase by homologues of bovine pancreatic trypsin inhibitor.

Biochemistry, 1996
The interactions of three BPTI homologues with human leukocyte elastase and porcine pancreatic elastase have been investigated. The principal mutation in determining the specificity of inhibition was the Lys15-Val mutation at the P1 position.
J. Kraunsoe, T. Claridge, G. Lowe
semanticscholar   +1 more source

Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.

Biochemistry, 1996
The crystal structure of a stoichiometric complex between an elastase-specific inhibitor elafin and porcine pancreatic elastase (PPE) has been determined and refined to a crystallographic R-factor of 19.7% at 1.9 A resolution.
M. Tsunemi   +3 more
semanticscholar   +1 more source

Radioimmunoassay of Human Pancreatic Elastase 1

Enzyme, 1983
A radioimmunoassay for determination of human pancreatic elastase 1 was developed and the interaction of pancreatic elastase 1 with serum protease inhibitors (alpha 2-macroglobulin and alpha 1-antitrypsin) was investigated. Gel filtration studies showed that immunoreactive elastase 1 was present in serum and intact plasma as a complex with alpha 1 ...
Michio Ogawa   +5 more
openaire   +3 more sources

Pancreatic elastase activates pulmonary nuclear factor kappa B and inhibitory kappa B, mimicking pancreatitis-associated adult respiratory distress syndrome.

Surgery, 2000
BACKGROUND Select pancreatic enzymes, primarily elastase, precipitate pulmonary injury similar to pancreatitis-associated adult respiratory distress syndrome and stimulate leukocyte cytokine production in vitro via nuclear factor kappa B (NF-kappaB ...
Colleen E Jaffray   +4 more
semanticscholar   +1 more source

Pancreatic ductal cell carcinoma producing pancreatic elastase 1

Journal of Surgical Oncology, 1993
AbstractThe elevation of plasma pancreatic elastase 1 in patients with pancreatic cancer is caused by concomitant pancreatitis. There is no report that pancreatic ductal cell carcinoma tissue itself produced elastase 1. A 54‐year‐old woman underwent total pancreatectomy for pancreatic ductal cell carcinoma.
Yasuhiro Tanaka   +5 more
openaire   +3 more sources

Diagnostic significance of immunological assay of pancreatic elastases in acute pancreatitis

Clinical Biochemistry, 1983
Pancreatic elastases have been assumed to be implicated in the pathogenesis of the vascular injury in acute hemorrhagic pancreatitis. We reported the purification and some properties of human pancreatic elastases. In the present study, the value of the determination of serum pancreatic elastases was investigated.
Goro Kosaki   +5 more
openaire   +3 more sources

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