Results 1 to 10 of about 21,402 (206)

Pancreatic endocrine and exocrine function in children following near-total pancreatectomy for diffuse congenital hyperinsulinism. [PDF]

PLoS ONE, 2014
ContextCongenital hyperinsulinism (CHI), the commonest cause of persistent hypoglycaemia, has two main histological subtypes: diffuse and focal. Diffuse CHI, if medically unresponsive, is managed with near-total pancreatectomy.
Ved Bhushan Arya, Senthil Senniappan, Huseyin Demirbilek, Syeda Alam, Sarah E Flanagan, Sian Ellard, Khalid Hussain   +6 more
doaj   +2 more sources

Nivolumab-Induced Exocrine Pancreatic Insufficiency [PDF]

Case Reports in Oncology, 2021
Immunotherapy is increasingly gaining applicability for several malignancies. While the survival of several malignancies has dramatically improved, immune-related adverse events (irAEs) can occur and can cause severe damage to patients. Side effects such
Boudewijn Sweep, Sofie Wilgenhof, Sander Anten   +2 more
doaj   +5 more sources

Consensus for the management of pancreatic exocrine insufficiency: UK practical guidelines [PDF]

BMJ Open Gastroenterology, 2021
Introduction Pancreatic exocrine insufficiency is a finding in many conditions, predominantly affecting those with chronic pancreatitis, pancreatic cancer and acute necrotising pancreatitis.
John S Leeds, Andrew D Hopper, Rajesh Kumar, Keith J Roberts, Mary E Phillips, Laura McGeeney, Sinead N Duggan   +6 more
doaj   +2 more sources

Secondary exocrine pancreatic insufficiency. Features of the choice of the enzyme

Медицинский совет, 2021
Exocrine pancreatic insufficiency is quite common in clinical practice of doctors of many specialties. Decrease in intraduodenal lipase levels below 5–10% of normal leads to pancreatic steatorrhea, weight loss and a potential decrease in quality of life.
I. G. Pakhomova
doaj   +1 more source

Pancreatic fibrosis correlates with exocrine pancreatic insufficiency after pancreatoduodenectomy [PDF]

, 2008
Background: Obstruction of the pancreatic duct can lead to pancreatic fibrosis. We investigated the correlation between the extent of pancreatic fibrosis and the postoperative exocrine and endocrine pancreatic function.
Dekken, H. (Herman) van, Eijck, C.H.J. (Casper) van, Hof, G. van 't, Hop, W.C.J. (Wim), Kazemier, G. (Geert), Pek, C.J. (Chulja), Toorenenbergen, A.W. (Albert) van, Tran, T.C.K. (Khe)   +7 more
core   +8 more sources

Current and Future Therapeutic Approaches of Exocrine Pancreatic Insufficiency in Children with Cystic Fibrosis in the Era of Personalized Medicine

Pharmaceutics, 2023
This review presents current updates of pancreatic enzyme replacement therapy in children with cystic fibrosis based on literature published in the last decade and some special considerations regarding pancreatic enzyme replacement therapy in the era of ...
Mirela-Elena Ritivoiu, Cristina Manuela Drăgoi, Dumitru Matei, Iustina Violeta Stan, Alina Crenguţa Nicolae, Mihai Craiu, Ion-Bogdan Dumitrescu, Alina Angelica Ciolpan   +7 more
doaj   +1 more source

Pancreatic exocrine insufficiency in diabetes mellitus

Сахарный диабет, 2023
Diabetes is disease of both the endo- and exocrine parts of the pancreas. Pancreatic exocrine insufficiency (PEI) can occur in every 2–3 patients with diabetes and affect not only the quality, but also life expectancy. At the same time, the diagnosis and
M. V. Shestakova, I. V. Maev, A. S. Ametov, M. B. Antsiferov, D. S. Bordin, G. R. Galstyan, F. K. Dzgoeva, Y. A. Kucheryavyy, A. M. Mkrtumyan, T. V. Nikonova, E. Y. Pashkova   +10 more
doaj   +1 more source

Clinical and pharmacological approaches to the management of exocrine pancreatic insufficiency in chronic pancreatitis

Медицинский совет, 2021
Chronic pancreatitis is a multifactorial disease in which repeated episodes of inflammation of the pancreas contribute to the development of fibrous tissue, leading to chronic pain, as well as exocrine and endocrine insufficiency.
V. N. Drozdov, E. V. Shikh, A. A. Astapovskiy, Yu. V. Kotlyachkova, L. E. Dobrovolskaya, A. K. Starodubtsev, I. A. Komissarenko, S. Y. Serebrova   +7 more
doaj   +1 more source

A retrospective review of α-gal syndrome complicating the management of suspected pancreatic exocrine insufficiency in one gastroenterology clinic in central Virginia

Frontiers in Gastroenterology, 2023
The galactose-α-1,3-galactose (α-gal) mammalian meat allergy, α-gal syndrome, often includes diarrhea, abdominal pain, and other gastrointestinal (GI) symptoms. Pancreatic exocrine insufficiency causes similar symptoms. The pancreatic replacement enzymes,
Nathan E. Richards, Jeffrey M. Wilson, Thomas A. E. Platts-Mills, Robert D. Richards   +3 more
doaj   +1 more source

Congenital etiologies of exocrine pancreatic insufficiency

Frontiers in Pediatrics, 2022
Congenital exocrine pancreatic insufficiency is a rare condition. In a vast majority of patients, exocrine dysfunction occurs as part of a multisystemic disease, the most prevalent being cystic fibrosis and Shwachman-Bodian-Diamond syndrome.
Isabelle Scheers, Silvia Berardis
doaj   +1 more source