Results 221 to 230 of about 116,954 (354)

Safety and efficacy of the therapy with CD4 + CD25highCD127‐T regulatory cells: When paediatric patient becomes adult

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1392-1402, February 2026.
Abstract Aim CD4 + CD25highCD127‐T regulatory cells (Tregs) remain a drug candidate for immunotherapy of type 1 diabetes. We completed three trials testing Tregs in recently diagnosed type 1 diabetes children. Here, we looked for long‐term safety and efficacy aspects important in the authorisation of this therapy.
Marta Bandura, Magdalena Piotrowska‐Mieczkowska, Matylda Hennig, Mateusz Gliwiński, Anna Wołoszyn‐Durkiewicz, Julia Schoenhoff, Milena Dybowska, Anna Alska, Piotr Gutknecht, Bartosz Trzeciak, Katarzyna Stefańska, Paulina Glasner, Marcin Hellmann, Jacek Burzyński, Arkadiusz Michalak, Janusz Siebert, Dorota Iwaszkiewicz‐Grześ, Małgorzata Myśliwiec, Piotr Trzonkowski   +18 more
wiley   +1 more source

Effects of endurance exercise training on endoplasmic reticulum stress in pancreatic islets of obese mice. [PDF]

Braz J Med Biol Res
Marconato-Júnior E, Soares GM, Rodrigues-Dos-Santos K, Araujo TDR, Vettorazzi JF, Zangerolamo L, Costa-Junior JM, Carneiro EM, Boschero AC, Barbosa HCL.   +9 more
europepmc   +1 more source

Pancreatic Islet Transplantation: State of the Art and Future Perspectives

, 2019
Gianluca Donatini, Sébastien Giraud, Jean‐Louis Kraimps, J. Danion, Thierry Hauet   +4 more
openalex   +1 more source

Lymphoid Organs Remodeling in Non‐Obese Diabetic Goto‐Kakizaki Rats Immunized With SARS‐CoV‐2 Antigens

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
The Goto‐Kakizaki rat, a non‐obese model of type 2 diabetes mellitus (T2DM), exhibits lymphoid organ remodeling, including baseline thymic involution and splenic white pulp reorganization. Following completion of a three‐dose SARS CoV‐2 antigen immunization protocol, anti‐Spike IgG levels were significantly increased despite these structural changes ...
Sara Araujo Pereira, Mariana Cruz Lazzarin, Maria Lucia Zaidan Dagli, Bianca de Carvalho Lins Fernandes Távora, Eliana Faquim de Lima Mauro, Marcelo Larami Santoro, Sandra Coccuzzo Sampaio Vessoni, Luis Roberto de Camargo Gonçalves, Marina Sakamoto Sotoyama, Ricardo das Neves Oliveira, Vania Gomes de Moura Mattaraia, Rui Curi   +11 more
wiley   +1 more source

Histomorphogenesis of human pancreatic islets amidst maternal anaemia: a critical insight. [PDF]

Anat Cell Biol
Babu S, Mishra PR, Ravi PK, Swain S, Begum J, Patnaik M.   +5 more
europepmc   +1 more source

Electron microscopic observation of the primary cilium in the pancreatic islets.

, 1986
Masao Yamamoto, Katsuko Kataoka
openalex   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles, Yubo Wang, Kathryn Rhodes, Sharon DeMorrow   +3 more
wiley   +1 more source

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets. [PDF]

Adv Sci (Weinh)
Yu XX, Peng P, Wang YN, He MY, He S, Jin CT, Yang L, Wang X, Zheng JX, Gao J, Xu CR.   +10 more
europepmc   +1 more source

Contents and secretion of glucagon and insulin in rat pancreatic islets from the viewpoint of their localization in pancreas.

, 1989
YOSHIMASA TASAKA, Hiroshi Matsumoto, Yukiko Inoue, Yukimasa Hirata   +3 more
openalex   +2 more sources

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, Volume 600, Issue 2, Page 140-163, January 2026.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source