Results 51 to 60 of about 53,803 (167)

Features of the alpha-cell population organization in pancreas of spontaneously hypertensive rats (SHR)

open access: yesPatologìâ, 2017
Alpha cells of pancreatic islets constitute the second largest population of pancreatic endocrinocytes, and the glucagon synthesized in them plays an important role in the regulation of glucose homeostasis.
T. V. Abramova, Yu. M. Kolesnyk
doaj   +1 more source

Generation of ARX-T2A-H2B-CFP x C-PEP-mCherry-hiPSC double reporter line for monitoring of pancreatic differentiation

open access: yesStem Cell Research
Pancreatic islets consist of several different endocrine cell types that work in harmony. Aside from primary pancreatic islets, stem cell-derived pancreatic islets can be used as an alternative research and disease model.
Eunike Sawitning Ayu Setyono   +4 more
doaj   +1 more source

Bioprinting of bespoke islet-specific niches to promote maturation of stem cell-derived islets

open access: yesNature Communications
Pancreatic islets are densely packed cellular aggregates containing various hormonal cell types essential for blood glucose regulation. Interactions among these cells markedly affect the glucoregulatory functions of islets along with the surrounding ...
Myungji Kim   +6 more
doaj   +1 more source

Gelatin Density Gradient for Isolation of Islets of Langerhans

open access: yesCell Transplantation, 1998
Isolation of islets of Langerhans (islets) has been performed by means of collagenase digestion of the pancreatic tissue combined with density gradient separation of islets from unwanted exocrine tissues.
Tadashi Samejima   +4 more
doaj   +1 more source

Tumors of the pancreatic islets [PDF]

open access: yesCancer, 1960
J, SIERACKI, R B, MARSHALL, R C, HORN
openaire   +2 more sources

Distributions of endocrine cell clusters during porcine pancreatic development.

open access: yesPLoS ONE, 2019
BackgroundPancreatic islet xenotransplantation is a potential treatment for diabetes mellitus, and porcine pancreas may provide a readily available source of islets.
Masaki Nagaya   +10 more
doaj   +1 more source

Immunohistochemical distribution of insulin-, glucagon- and somatostatin-containing cells in the pancreas of Lake Van fish (Alburnus tarichi Güldenstädt, 1814) (Cyprinidae)

open access: yesEuropean Journal of Histochemistry, 2019
The Lake Van fish (Alburnus tarichi) is a species that is endemic to Turkey’s Lake Van basin. In this study, the regional distribution, volume density, and relative frequency of some pancreatic endocrine cells in Lake Van fish were investigated via ...
Burak Kaptaner
doaj   +1 more source

Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

open access: yesPLoS ONE, 2022
Aims The transcriptome of different dissociated pancreatic islet cells has been described in enzymatically isolated islets in both health and disease. However, the isolation, culturing, and dissociation procedures likely affect the transcriptome profiles,
Louise Granlund   +4 more
doaj  

The features of beta-cells organization in the pancreas of spontaneously hypertensive rat (SHR)

open access: yesPatologìâ, 2016
The control of b-cells pool in patients with hypertension is an actual problem, as it is possible that the hereditary genetic defects of arterial hypertension formation may affect the mechanisms of endocrine cell mass maintenance in pancreas and cause ...
T. V. Abramova, Yu. M. Kolesnyk
doaj   +1 more source

Revisiting pancreatic islet isolation in murine models: A practical and effective technical protocol

open access: yesPhysiological Reports
The endocrine pancreas is composed of clusters of cell groups called pancreatic islets. These cells are responsible for the synthesis and secretion of hormones crucial for glycemic homeostasis, such as insulin and glucagon.
Aline Fernandes‐da‐Silva   +3 more
doaj   +1 more source

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