Results 31 to 40 of about 53,803 (167)
A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment
Scientific Reports, 2022 Extracellular matrix (ECM) plays a multitude of roles, including supporting cells through structural and biochemical interactions. ECM is damaged in the process of isolating human islets for clinical transplantation and basic research.
Daniel M. Tremmel +10 more
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Pancreatic islet transplantation
Seminars in Pediatric Surgery, 2012 Pancreatic islet transplantation is a minimally invasive treatment that has the potential to prevent diabetes after total pancreatectomy for benign disease (islet autotransplantation) and to reverse diabetes in those with type 1 diabetes (islet allotransplantation).
Johnson, P, Jones, K
openaire +2 more sources
Acta Scientiarum: Biological Sciences, 2013 Activation of β2 adrenergic receptors by catecholamine or catecholamine-mimetic substances may enhance insulin secretion. We herein investigated KCl- and nutrient-stimulated insulin secretion in pancreatic islets isolated from β2 knockout (β2KO) mice ...
Anderson Carlos Marçal +5 more
doaj +1 more source
Microgravity Effect on Pancreatic Islets. [PDF]
CellsWe previously demonstrated that boundary cap neural crest stem cells (BCs) induce the proliferation of beta-cells in vitro, increase survival of pancreatic islets (PIs) in vivo after transplantation, and themselves strongly increase their proliferation capacity after exposure to space conditions.
Zeger L +8 more
europepmc +7 more sources
Metabolomics applied to the pancreatic islet [PDF]
Archives of Biochemistry and Biophysics, 2016 Metabolomics, the characterization of the set of small molecules in a biological system, is advancing research in multiple areas of islet biology. Measuring a breadth of metabolites simultaneously provides a broad perspective on metabolic changes as the islets respond dynamically to metabolic fuels, hormones, or environmental stressors.
Jessica R, Gooding +2 more
openaire +2 more sources
Imaging of pancreatic islet cells [PDF]
Diabetes/Metabolism Research and Reviews, 2011 AbstractAt present, the onset and progress of diabetes, and the efficacy of potential treatments, can only be assessed through indirect means, i.e. blood glucose, insulin, or C‐peptide measurements. The development of non‐invasive and reliable methods for (1) quantification of pancreatic beta islet cell mass in vivo, (2) determining endogenous islet ...
Dian R, Arifin, Jeff W M, Bulte
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Вестник трансплантологии и искусственных органов, 2022 The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva +3 more
doaj +1 more source
Tolerance and pancreatic islet transplantation [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001 Islet transplantation holds renewed promise as a cure for type I diabetes mellitus. Results of recent clinical trials have shown remarkable success, and have reignited universal optimism for this procedure. In spite of this success, the need for life–long immunosuppression of the recipient still limits islet transplantation to patients with poorly ...
L, Inverardi, C, Ricordi
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Antioxidants, 2023 Our laboratory previously revealed that regenerating islets-derived protein 2 (REG2) was diminished in pancreatic islets of glutathione peroxidase-1-overexpressing mice (Gpx1-OE).
Hong Wang +3 more
doaj +1 more source
A histomorphometric study of pancreatic islets in the mature domestic duck of western Iran [PDF]
Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2008 The aim of this study is to determine the diameter and number of pancreatic islets of the duck. Histomorphometric studies were carried out on the pancreas of adult male and female domestic ducks of western Iran with an average age of 26-30 weeks using ...
B Mobini
doaj