Results 21 to 30 of about 53,803 (167)
A high concentration of gamma-aminobutyric acid (GABA) and a high activity of glutamate decarboxylase (GAD), enzyme for GABA synthesis, were demonstrated in the rat pancreatic islets using a recently developed assay method combining the GABase system with the enzymatic NADP-NADPH cyclin method. Both GABA concentration and GAD activity in the pancreatic
TANIGUCHI, Hiroshi +3 more
openaire +3 more sources
Data on morphometric analysis of the pancreatic islets from C57BL/6 and BALB/c mice
The endocrine portion of the pancreas, which is characterized by pancreatic islets, has been widely investigated among different species. The BALB/c and C57BL/6 mice are extensively used in experimental research, and the morphometric differences in the ...
Thiago Aparecido da Silva +4 more
doaj +1 more source
Creation of a bioartificial pancreas, including a cell-engineered construct (CEC) formed from pancreatic islets (islets of Langerhans) and a biocompatible matrix mimicking the native microenvironment of pancreatic tissue, is one of the approaches to the ...
A. S. Ponomareva +9 more
doaj +1 more source
Variability of pancreatic donors may significantly impact the success of islet isolation. The aim of this study was to evaluate donor factors associated with isolation failure and to investigate whether immunohistology could contribute to organ selection.
Zuzana Berkova +16 more
doaj +1 more source
Microencapsulation of pancreatic islets represents a potentially effective method to prevent graft rejection in allotransplantation or xenotransplantation without the need of immunosuppression.
Wenjing Wang +8 more
doaj +1 more source
Recently, tissue engineering, including 3D bioprinting of the pancreas, has acquired clinical significance and has become an outstanding potential method of customized treatment for type 1 diabetes mellitus. The study aimed to evaluate the function of 3D-
Marta Klak +14 more
doaj +1 more source
Heterogeneity of the Human Pancreatic Islet [PDF]
Pancreatic β-cells play a pivotal role in maintaining normoglycemia. Recent studies have revealed that the β-cell is not a homogeneous cell population but, rather, is heterogeneous in a number of properties such as electrical activity, gene expression, and cell surface markers.
Michael P. Dybala, Manami Hara
openaire +2 more sources
Dexamethasone during pregnancy impairs maternal pancreatic β-cell renewal during lactation
Pancreatic islets from pregnant rats develop a transitory increase in the pancreatic β-cell proliferation rate and mass. Increased apoptosis during early lactation contributes to the rapid reversal of those morphological changes.
Caio Jordão Teixeira +5 more
doaj +1 more source
Pancreatic Islet Transplantation
Islet transplantation offers hope to many patients with diabetes, who envision a life free of glucose checks and insulin injections. What are the barriers to its widespread implementation?
Mark A Naftanel, David M Harlan
openaire +4 more sources
Insulin-synthesizing cells (ISCs) of pancreatic gland are localized both in its islets, and in exocrine portion, as single cells or cellular agglomerates.
T. S. Bulavintseva +3 more
doaj +1 more source

