Results 11 to 20 of about 53,803 (167)
Pancreatic islet transplantation [PDF]
Diabetology & Metabolic Syndrome, 2009 No formulation of exogenous insulin available to date has yet been able to mimic the physiological nictemeral rhythms of this hormone, and despite all engineering advancements, the theoretical proposal of developing a mechanical replacement for pancreatic beta cell still has not been reached.
Corrêa-Giannella Maria +1 more
openaire +5 more sources
Irisin—A Pancreatic Islet Hormone [PDF]
Biomedicines, 2022 Irisin is a myokine involved in glucose homeostasis. It is primarily expressed in skeletal muscle, but also in the pancreas. This study aimed to elucidate its presence and role in the islets of Langerhans—i.e., its effect on insulin and glucagon secretion as well as on blood flow in the pancreas.
Daniel Norman +3 more
openaire +5 more sources
Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells. [PDF]
PLoS ONE, 2015 The local synthesis of dopamine and its effects on insulin release have been described in isolated islets. Thus, it may be accepted that dopamine exerts an auto-paracrine regulation of insulin secretion from pancreatic beta cells.
Maria Jose Garcia Barrado +7 more
doaj +1 more source
The Protective Impact of Lycopene and Folic Acid Supplementation Against Nicotine Toxicity on Pancreatic Islets in Adult Male Albino Rats: Biochemical and Immuno-Histochemical Study [PDF]
The Egyptian Journal of Histology, 2023 Introduction: It is reported that dysfunctioning of islets and elevated levels of fasting blood glucose are found in rats exposed to nicotine. Lycopene is thought to have a potential role as an effective antioxidant in the prevention of chronic diseases ...
mai Ibrahim, nehal shaheen
doaj +1 more source
Glucose transporters in pancreatic islets [PDF]
Pflügers Archiv - European Journal of Physiology, 2020 AbstractThe fine-tuning of glucose uptake mechanisms is rendered by various glucose transporters with distinct transport characteristics. In the pancreatic islet, facilitative diffusion glucose transporters (GLUTs), and sodium-glucose cotransporters (SGLTs) contribute to glucose uptake and represent important components in the glucose-stimulated ...
Constantin Berger, Daniela Zdzieblo
openaire +3 more sources
Micromachines, 2021 Background: 3D bioprinting is the future of constructing functional organs. Creating a bioactive scaffold with pancreatic islets presents many challenges. The aim of this paper is to assess how the 3D bioprinting process affects islet viability. Methods:
Marta Klak +12 more
doaj +1 more source
PLoS Biology, 2022 Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D).
Volodymyr Petrenko +6 more
doaj +2 more sources
Digital Imaging as a Possible Approach in Evaluation of Islet Yield
Cell Transplantation, 2003 Digital image analysis (DIA) is a new method in assessment of islet amount, which is expected to provide reliable and consistent results. We compared this method with conventional counting of small numbers of rat islets.
Peter Girman +3 more
doaj +1 more source
Journal of Materials Science: Materials in Medicine, 2022 Bioengineered pancreatic β-islets have been widely advocated for the research and treatment of diabetes by offering both suitable cell culture models for the study of the pathology and the testing of new drugs and a therapy in those patients no longer ...
Valeria Perugini +2 more
doaj +1 more source
PanCircBase: An online resource for the exploration of circular RNAs in pancreatic islets
Frontiers in Cell and Developmental Biology, 2022 Circular RNAs (circRNAs) are a novel class of covalently closed RNA molecules that recently emerged as a critical regulator of gene expression in development and diseases.
Tanvi Sinha +5 more
doaj +1 more source