Results 131 to 140 of about 861,721 (390)

Mucinous Cystic Neoplasm of the Pancreas is Not an Aggressive Entity [PDF]

, 2014
Objective: Mucinous cystic neoplasms (MCNs) of the pancreas have often been confused with intraductal papillary mucinous neoplasms. We evaluated the clinicopathologic characteristics, prevalence of cancer, and prognosis of a large series of well ...
Bassi, Claudio, Capelli, Paola, Castillo, Carlos Fernández-del, Crippa, Stefano, Domínguez, Ismael, Falconi, Massimo, Lauwers, Gregory Y., Mino-Kenudson, Mari, Pederzoli, Paolo, Salvia, Roberto, Thayer, Sarah P., Warshaw, Andrew Louis, Zamboni, Giuseppe   +12 more
core   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

What Is New in the 2017 World Health Organization Classification and 8th American Joint Committee on Cancer Staging System for Pancreatic Neuroendocrine Neoplasms?

Korean Journal of Radiology, 2018
The diagnosis and management of pancreatic neuroendocrine neoplasms (NENs) have evolved significantly in recent years. There are several diagnostic and therapeutic challenges and controversies regarding the management of these lesions. In this review, we
J. Choe, Kyung Won Kim, Hyoung-Jung Kim, Dong Wook Kim, Kyu Pyo Kim, Seung‐Mo Hong, J. Ryu, S. Tirumani, K. Krajewski, N. Ramaiya   +9 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Cancer Informatics for Cancer Centers (CI4CC): Building a Community Focused on Sharing Ideas and Best Practices to Improve Cancer Care and Patient Outcomes. [PDF]

, 2020
Cancer Informatics for Cancer Centers (CI4CC) is a grassroots, nonprofit 501c3 organization intended to provide a focused national forum for engagement of senior cancer informatics leaders, primarily aimed at academic cancer centers anywhere in the world
Barnholtz-Sloan, Jill S, Basu, Amrita, Borowsky, Alexander D, Bui, Alex, DiGiovanna, Jack, Garcia-Closas, Montserrat, Genkinger, Jeanine M, Gerke, Travis, Induni, Marta, Kibbe, Warren A, Lacey, James V, Jr, Mirel, Lisa, Nadaf, Sorena, Permuth, Jennifer B, Rollison, Dana E, Saltz, Joel, Shenkman, Elizabeth A, Ulrich, Cornelia M, Zheng, W Jim   +18 more
core  

Pancreatic Mucinous Cystic Neoplasms with Sarcomatous Stroma: Molecular Evidence for Monoclonal Origin with Subsequent Divergence of the Epithelial and Sarcomatous Components [PDF]

, 2000
Wiebren van den Berg, Metin Tascilar, G.J.A. Offerhaus, Jorge Albores‐Saavedra, Bruce M. Wenig, Ralph H. Hruban, Edward Gabrielson   +6 more
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Hepatobiliary and Pancreatic neoplasms in patients with McCune-Albright syndrome.

Journal of Clinical Endocrinology and Metabolism, 2014
BACKGROUND McCune-Albright syndrome (MAS), which includes polycystic fibrous dysplasia, precocious puberty, and café au lait spots, is a rare disorder caused by somatic activating mutations of the GNAS gene.
S. Gaujoux, S. Salenave, M. Ronot, A. Rangheard, J. Cros, J. Belghiti, A. Sauvanet, P. Ruszniewski, P. Chanson   +8 more
semanticscholar   +1 more source

Neoplasms of the Ampulla of Vater with Concurrent Pancreatic Intraductal Neoplasia: A Histological and Molecular Study [PDF]

, 2001
S. Nicholas Agoff, David A. Crispin, Mary P. Bronner, David H. Dail, Stephen E. Hawes, Rodger C Haggitt   +5 more
openalex   +1 more source