Results 151 to 160 of about 1,020,663 (289)

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source

Subtype-associated complexity and prognostic significance of the NLRP3 inflammasome landscape in pancreatic neoplasms. [PDF]

J Pathol Clin Res
Németh K, Mezei E, Vörös J, Borka K, Pesti A, Kenessey I, Kiss A, Budai A.   +7 more
europepmc   +1 more source

Endobody: Genetically Encodable Nanobody‐CPP Chimeras for Degradation of Membrane and Extracellular Proteins

Advanced Science, EarlyView.
We introduced genetically encodable, receptor‐independent nanobody‐CPP chimeras, termed endobodies, as robust and modular membrane protein degraders. Additionally, proteasome‐targeting domain (PTD)‐tethered endobody demonstrates further enhanced degradation potency.
Chengjian Zhou, Huiping He, Simin Xia, Xi Chen   +3 more
wiley   +1 more source

Ossification in pancreatic neoplasms: A report of three cases of neuroendocrine tumor, mucinous cystic neoplasm, and intraductal papillary mucinous neoplasm with review of the literature. [PDF]

Biomed Rep
Fukuma Y, Ishida M, Yasuda E, Nakanishi K, Kushiyama S, Tomioka A, Asakuma M, Hirose Y.   +7 more
europepmc   +1 more source

Pancreaticoduodenectomy for the treatment of pancreatic neoplasms in children: A Pediatric Surgical Oncology Research Collaborative study. [PDF]

Pediatr Blood Cancer, 2020
Vasudevan SA, Ha TN, Zhu H, Heaton TE, LaQuaglia MP, Murphy JT, Barry WE, Goodhue C, Kim ES, Aldrink JH, Polites SF, Leraas HJ, Rice HE, Tracy ET, Lautz TB, Superina RA, Davidoff AM, Langham MR, Murphy AJ, Bütter A, Davidson J, Glick RD, Grijalva J, Gow KW, Ehrlich PF, Newman EA, Lal DR, Malek MM, Le-Nguyen A, Piché N, Rothstein DH, Short SS, Meyers R, Dasgupta R.   +33 more
europepmc   +1 more source

Cystic pancreatic neoplasms in a tertiary gastroenterologic referral center: Evaluation of the diagnostic accuracy of endoscopic ultrasound, progression rate and malignancy rate in a large unicentric cohort. [PDF]

Z Gastroenterol, 2023
Schedel J, Kaess M, Schorr W, Brookman-Amissah D, Alqahtan S, Pech O.   +5 more
europepmc   +1 more source

HLA‐DR+ Schwann Cells Generate the Protumor Cancer‐Neuron‐Immune Niche in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
Hijacked and educated by HNSCC cells, HLA‐DR+ Schwann cells lost their normal neural‐related functions but acquired immunoregulatory phenotypes to promote CD4+ T cells transform into Tregs. HLA‐DR+ Schwann cells induced a macrophage subpopulation, Il1β.
Xiaoyan Meng, Zhonglong Liu, Shijian Zhang, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He   +7 more
wiley   +1 more source

Synchronous Pancreatic Neoplasms Involving Pancreatic Ductal Adenocarcinoma: A Systematic Review of Case Reports. [PDF]

J Pers Med
Paramythiotis D, Karlafti E, Tsavdaris D, Mekras A, Ioannidis A, Panidis S, Psoma E, Prassopoulos P, Michalopoulos A.   +8 more
europepmc   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

The Brescia International Multidisciplinary Consensus Guidelines on the Optimal Pathology Assessment and Multidisciplinary Pathways of Non-Pancreatic Neoplasms in and Around the Ampulla of Vater (PERIPAN). [PDF]

United European Gastroenterol J
Abu Hilal M, Uijterwijk BA, Lemmers DHL, Janssen BV, Besselink MG, Bianchi D, Fariña A, Fukushima N, Gill AJ, Hong SM, Krasinskas A, Luchini C, Melocchi L, Rossi G, Scarpa A, Basturk O, Chatterjee D, Chou A, Esposito I, Feakins R, Groot Koerkamp B, Hruban RH, La Rosa S, Shi C, Singhi A, Verheij J, Wang H, Alfieri S, Ausania F, Alseidi A, Bruno MJ, Boggi U, Bnà C, Dervenis C, Falconi M, Ghidini M, Kist JW, Marchegiani G, Milella M, Salvia R, Siriwardena A, Wilmink H, Zaniboni A, Al-Janabi S, Holm MB, Roos E, Sano N, Song IH, Tarcan Z, Balzano G, Frigerio I, Guglielmi A, Malleo G, Asbun H, Adsay V, Verbeke C.   +55 more
europepmc   +1 more source