Results 171 to 180 of about 576,341 (292)

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

Intratumoral calcifications in pancreatic neoplasms on unenhanced CT: frequency and diagnostic implications. [PDF]

Radiol Med
De Robertis R, Brunese MC, Cardobi N, Spoto F, Pasquazzo F, Mascarin B, Urraro F, Reginelli A, Brunese L, Cappabianca S, D'Onofrio M.   +10 more
europepmc   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Central pancreatectomy: a Latin American experience of parenchyma-sparing surgery for benign and low-grade pancreatic neoplasms. [PDF]

Arq Bras Cir Dig
Conde-Monroy D, Namur GN, Tustumi F, Stolzemburg LCP, Jureidini R, Jukemura J, Ribeiro Junior U, Herman P, Ribeiro TC.   +8 more
europepmc   +1 more source

Pancreatic Neoplasm [PDF]

, 2020
openaire   +1 more source

Cystic pancreatic neoplasms: 12-year surgical experience

, 2006
Cystic pancreatic neoplasms have been increasingly diagnosed in the last years. Resection is recommended in most cases, but their management has not been standardized since an accurate nonoperative differentiation is often difficult.
Pasquale Lepiane, Fabio Carboni, Roberto Santoro, Roberto Lorusso, PROPOSITO, Delia, SPOLETINI, Domenico, Eugenio Santoro, R. Mancini   +7 more
core  

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Safety and Efficacy of Radiofrequency Ablation in Management of Various Pancreatic Neoplasms. [PDF]

J Clin Med
Goduguchinta V, Ebrahim M, Patel R, Randhawa N, Khalyfa A, Inamullah M, Desai R, Ayub K.   +7 more
europepmc   +1 more source

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

Advanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li, Zhanzhi Meng, Hongjun Yu, Yongliang Hua, Zihao Li, Bing Yin, Baolin Qian, Zhongyu Li, Yongzhi Zhou, Zhigang Feng, Shounan Lu, Shanjia Ke, Miaoyu Bai, Yao Fu, Wei Tang, Natalia V. Belosludtseva, Yong Ma   +16 more
wiley   +1 more source

Clinicopathologic risk factors for post-operative complications after enucleation of pancreatic neoplasms. [PDF]

World J Surg Oncol
Madeka I, Yi S, Evans J, Baek D, Naringrekar HV, Lavu H, Yeo CJ, Nevler A, Bowne WB.   +8 more
europepmc   +1 more source