Results 161 to 170 of about 297,195 (347)

Pancreatic Neoplasm in 2011: An Update

JOP : Journal of the pancreas, 2011
JOP. Journal of the Pancreas, Vol 12, No 4 (2011): July - p.
openaire   +2 more sources

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Artificial intelligence for screening and early diagnosis of pancreatic neoplasms in the context of centralization of the laboratory service in the region

Сибирский онкологический журнал
Objective. Determination of the optimal machine learning model for the creation of software for screening and early diagnosis of pancreatic neoplasms in the context of centralization of the laboratory service in the region. Material and Methods.
S. I. Panin, V. A. Suvorov, A. V. Zubkov, S. A. Bezborodov, A. A. Panina, N. V. Kovalenko, A. R. Donsckaia, I. G. Shushkova, A. V. Bykov, Ya. A. Marenkov   +9 more
doaj   +1 more source

Pancreatic Neoplasms: CT Evaluation of the Uncommon Presentations of Common Lesions and Common Presentations of the Uncommon Lesions! [PDF]

Indian J Radiol Imaging, 2022
Deshpande SS, Joshi AR, Mankar D.
europepmc   +1 more source

Pancreatic cyst fluid concentration of high-mobility group A2 protein acts as a differential biomarker of dysplasia in intraductal papillary mucinous neoplasm

, 2015
Christopher J. DiMaio, Frances Weis‐Garcia, Emilia Bagiella, Laura H. Tang, Peter J. Allen   +4 more
openalex   +1 more source

FBXO44 Regulates FOXP1 Degradation Through AURKA‐Dependent Phosphorylation to Promote Colorectal Cancer Progression

Advanced Science, EarlyView.
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie, Hengjie Xu, Sheng Yang, Chuanxin Tian, Tuo Wang, Chi Jin, Zhihao Chen, Xiaowei Wang, Junwei Tang, Yifei Feng, Yueming Sun   +10 more
wiley   +1 more source

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, EarlyView.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

Nomogram predicts CR-POPF in open central pancreatectomy patients with benign or low-grade malignant pancreatic neoplasms. [PDF]

Front Oncol, 2022
Ouyang L, Liu RD, Ren YW, Nie G, He TL, Li G, Zhou YQ, Huang ZP, Zhang YJ, Hu XG, Jin G.   +10 more
europepmc   +1 more source

OC.17.1 NATURAL HISTORY OF PANCREATIC INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS: CLINICAL EVALUATION OF SENDAI CRITERIA IN A LARGE COHORT OF PATIENTS

, 2014
Emanuele Dabizzi, Micaela Petrone, Mariaemilia Traini, Sabrina Gloria Giulia Testoni, P.A. Testoni, Paolo Giorgio Arcidiacono   +5 more
openalex   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source