Results 171 to 180 of about 4,592,636 (274)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Arecae pericarpium water extract alleviates chronic pancreatitis by deactivating pancreatic stellate cells. [PDF]

open access: yesFront Pharmacol, 2022
Kweon B   +7 more
europepmc   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Type 2 diabetes alters quiescent pancreatic stellate cells to tumor-prone state. [PDF]

open access: yesJCI Insight
Hara Y   +15 more
europepmc   +1 more source

Targeting pancreatic stellate cells in chronic pancreatitis: Focus on therapeutic drugs and natural compounds. [PDF]

open access: yesFront Pharmacol, 2022
Wu Y   +11 more
europepmc   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

open access: yesiNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang   +5 more
wiley   +1 more source

Microenvironment of pancreatic stellate cells in chronic pancreatitis

open access: yesWorld Chinese Journal of Digestology, 2017
Xiao-Hui Xiang, Shi-Hai Xia
openaire   +1 more source

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