Results 181 to 190 of about 271,582 (269)

TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function. [PDF]

Cell Rep Med
Alam MS, Gaida MM, Witzel HR, Otsuka S, Abbasi A, Guerin T, Abdelmaksoud A, Wong N, Cam MC, Kozlov S, Ashwell JD.   +10 more
europepmc   +1 more source

The occurrence of a fatal tuberculous pancreatic abscess simulating a pancreatic tumor in an immunocompromised patient. [PDF]

Germs, 2023
Benaissa E, Maleb A, Elouennass M.
europepmc   +1 more source

Cost‐Effective Identification of Hepatocellular Carcinoma from Cirrhosis or Chronic Hepatitis Virus Infection Using Eight Methylated Plasma DNA Markers

Advanced Science, EarlyView.
Early detection of hepatocellular carcinoma in patients with liver cirrhosis and/or hepatitis virus B/C infection improves survival. Through marker discovery, 8 methylated DNA markers are identified and a logistic regression model (COMET‐LR) is built in the training set, which achieved 90.0% sensitivity at 97.4% specificity in the validation set.
Tian Yang, Mingda Wang, Nanya Wang, Mingxin Pan, Yu Xu, Qiancheng You, Lanqing Yao, Jiahao Xu, Lihui Gu, Xiaodong Sun, Lei Zhang, Jiayue Xu, Bingsi Li, Guoqiang Wang, Shangli Cai, Guoyue Lv, Feng Shen   +16 more
wiley   +1 more source

CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival. [PDF]

Cancer Immunol Immunother
Wedig J, Jasani S, Mukherjee D, Lathrop H, Matreja P, Pfau T, D'Alesio L, Guenther A, Fenn L, Kaiser M, Torok MA, McGue J, Sizemore GM, Noonan AM, Dillhoff ME, Blaser BW, Frankel TL, Culp S, Hart PA, Cruz-Monserrate Z, Mace TA.   +20 more
europepmc   +1 more source

The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism

Advanced Science, EarlyView.
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang, Yi Xie, Shenglong Xia, Xinnuo Ge, Jiaying Li, Fang Liu, Fan Jia, Shengyao Wang, Qiao Zhou, Menghan Gao, Weihuan Fang, Chao Zheng   +11 more
wiley   +1 more source

Small Insulinoma Followed-up as an Indolent Pancreatic Tumor. [PDF]

Intern Med
Sato H, Fujii S, Okada T, Kawabata H, Kamikokura Y, Fujiya M.   +5 more
europepmc   +1 more source

Positive Feedback Regulation between KLF5 and XPO1 Promotes Cell Cycle Progression of Basal like Breast Cancer

Advanced Science, EarlyView.
KLF5 is highly expressed in BLBC patients and promotes Cyclin D1 and XPO1 transcription, ultimately leading to the inactivation of RB1. Both XPO1 inhibitor (KPT‐330) and CDK4/6 inhibitor (Palbociclib) can enhance RB1 activity and exert antitumor effects. It has been proved that the combination of KPT‐330 and Palbociclib can inhibit the proliferation of
Yu Tang, Rui Liu, Jing Zhu, Qian He, Chenglong Pan, Zhongmei Zhou, Jian Sun, Fubing Li, Longlong Zhang, Yujie Shi, Jing Yao, Dewei Jiang, Ceshi Chen   +12 more
wiley   +1 more source

Giant hemorrhagic pancreatic pseudocyst with suspected cystic pancreatic tumor: a case report. [PDF]

J Surg Case Rep
Nakatake R, Kitade H, Ishizaki M, Yanagida H, Okuyama T, Uemura Y, Sekimoto M.   +6 more
europepmc   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Impact of stroma remodeling on forces experienced by cancer cells and stromal cells within a pancreatic tumor tissue. [PDF]

Biomed Eng Online
Connaughton M, Dabagh M.
europepmc   +1 more source