RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis [PDF]
, 2016 Tumor suppression that is mediated by oncogene-induced senescence (OIS) is considered to function as a safeguard during development of pancreatic ductal adenocarcinoma (PDAC). However, the mechanisms that regulate OIS in PDAC are poorly understood. Here,
Algül, Hana +17 more
core +1 more source
Frontiers in Oncology, 2022 LAG-3 is one of the common tumor immune checkpoints. LAG-3 can inhibit the activation and proliferation of T cells, and can also suppress immunity by regulating other immune-related cell functions.
Qing Yan +9 more
doaj +1 more source
Collision of ductal adenocarcinoma and neuroendocrine tumor of the pancreas: a case report and review of the literature [PDF]
, 2017 Background: Simultaneous occurrence of exocrine and neuroendocrine tumors of the pancreas is very infrequent. We report a patient with an endocrine tumor in the pancreatic-duodenal area and extensive exocrine carcinoma involving the whole pancreas.
Blandamura, Stella +6 more
core +2 more sources
Skeletal muscle metastasis from extrahepatic cholangiocarcinoma: A case report and literature review
Frontiers in Surgery, 2022 BackgroundCholangiocarcinoma (CCA) is a type of malignant tumor that arises from the epithelium of the bile ducts. According to anatomical location, CCA can be classified as intrahepatic (ICC), perihilar (PCC), or extrahepatic (ECC).
Hongwei Qian +7 more
doaj +1 more source
Frontiers in Oncology, 2021 IgG4-related autoimmune cholangitis (IgG4-AIC) is often difficult to distinguish from cholangiocarcinoma (CCA). This study aimed to determine a practical clinical strategy for distinguishing between IgG4-AIC and CCA to avoid unnecessary surgical ...
Ke Zhu +7 more
doaj +1 more source
Cell-derived extracellular vesicles and membranes for tissue repair
Journal of Nanobiotechnology, 2021 Humans have a limited postinjury regenerative ability. Therefore, cell-derived biomaterials have long been utilized for tissue repair. Cells with multipotent differentiation potential, such as stem cells, have been administered to patients for the ...
Yuan Ding +7 more
doaj +1 more source
Early Detection and Localization of Pancreatic Cancer by Label-Free Tumor Synthesis [PDF]
arXiv, 2023 Early detection and localization of pancreatic cancer can increase the 5-year survival rate for patients from 8.5% to 20%. Artificial intelligence (AI) can potentially assist radiologists in detecting pancreatic tumors at an early stage. Training AI models require a vast number of annotated examples, but the availability of CT scans obtaining early ...
arxiv
Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications. [PDF]
, 2005 Background: Diabetes mellitus is associated with pancreatic cancer in more than 80% of the cases. Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere ...
BALDO G +11 more
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Improved Pancreatic Tumor Detection by Utilizing Clinically-Relevant Secondary Features [PDF]
arXiv, 2022 Pancreatic cancer is one of the global leading causes of cancer-related deaths. Despite the success of Deep Learning in computer-aided diagnosis and detection (CAD) methods, little attention has been paid to the detection of Pancreatic Cancer. We propose a method for detecting pancreatic tumor that utilizes clinically-relevant features in the ...
arxiv
Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice [PDF]
, 2014 Kristyn A Liu1†, Laura M Lashinger1†, Audrey J Rasmussen1† and Stephen D Hursting12* Author Affiliations 1 Department of Nutritional Sciences, University of Texas at Austin, Austin, TX 78723, USA 2 Department of Molecular Carcinogenesis, University ...
Hursting, Stephend D. +3 more
core +1 more source