Results 31 to 40 of about 1,718,006 (300)
Frontiers in Oncology, 2022 LAG-3 is one of the common tumor immune checkpoints. LAG-3 can inhibit the activation and proliferation of T cells, and can also suppress immunity by regulating other immune-related cell functions.
Qing Yan +9 more
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Frontiers in NutritionBackground and aimsMalnutrition is a well-recognized predictor of poor prognosis in malignancies. Recent studies suggest that the geriatric nutritional risk index (GNRI) is a more accurate determinant of prognosis in elderly patients than conventional ...
Sheng Wang +10 more
doaj +1 more source
Autoimmune pancreatitis mimicking pancreatic tumor [PDF]
Journal of Surgical Case Reports, 2012 Autoimmune pancreatitis (AIP) is a rare disease of unknown pathomechanism. It belongs to the IgG4-related disease family and responds well to steroids, although the relapse rate can reach up to 20-30%. Differentiating AIP from the more common pancreatic cancer can be very challenging.
Dede, Kristóf +4 more
openaire +2 more sources
Journal of PancreatologyObjective:. Pancreatic cancer is one of the most aggressive malignancies, a robust prognostic signature and novel biomarkers are urgently needed for accurate stratification of the patients and optimization of clinical decision-making. Methods:. A list of
Chengcheng Wang +7 more
doaj +1 more source
Skeletal muscle metastasis from extrahepatic cholangiocarcinoma: A case report and literature review
Frontiers in Surgery, 2022 BackgroundCholangiocarcinoma (CCA) is a type of malignant tumor that arises from the epithelium of the bile ducts. According to anatomical location, CCA can be classified as intrahepatic (ICC), perihilar (PCC), or extrahepatic (ECC).
Hongwei Qian +7 more
doaj +1 more source
Clinical Strategies Targeting the Tumor Microenvironment of Pancreatic Ductal Adenocarcinoma
, 2022 Pancreatic cancer has a complex tumor microenvironment which engages in extensive crosstalk between cancer cells, cancer-associated fibroblasts, and immune cells. Many of these interactions contribute to tumor resistance to anti-cancer therapies.
Christine Alewine +7 more
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Molecular mechanisms of drug resistance, invasion and metastasis in pancreatic carcinoma [PDF]
, 2008 The research outlined in this thesis aims to further our knowledge of the biological characteristics underlying the aggressive behaviour by which pancreatic cancer invades and metastasises at an early stage and is refractory to most chemotherapeutic ...
Walsh, Naomi
core +2 more sources
Organoids in cancer therapy: translational applications and clinical promise
Molecular CancerCancer remains a leading cause of mortality worldwide, with its management challenged by profound biological complexity and substantial intratumoral and interpatient heterogeneity.
Mingzhen Bai +11 more
doaj +1 more source
Cell-derived extracellular vesicles and membranes for tissue repair
Journal of Nanobiotechnology, 2021 Humans have a limited postinjury regenerative ability. Therefore, cell-derived biomaterials have long been utilized for tissue repair. Cells with multipotent differentiation potential, such as stem cells, have been administered to patients for the ...
Yuan Ding +7 more
doaj +1 more source
Frontiers in Oncology, 2021 IgG4-related autoimmune cholangitis (IgG4-AIC) is often difficult to distinguish from cholangiocarcinoma (CCA). This study aimed to determine a practical clinical strategy for distinguishing between IgG4-AIC and CCA to avoid unnecessary surgical ...
Ke Zhu +7 more
doaj +1 more source