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Endocrine Pancreatic Tumors [PDF]
Neuroendocrine tumors of the pancreas are rare neoplasms that may arise sporadically or in association with a hereditary endocrine neoplasia syndrome. Effective management requires directed biochemical testing, careful choice of preoperative imaging tests, and complete pancreatic exploration by an experienced endocrine surgeon utilizing intraoperative ...
T C, Lairmore, J F, Moley
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Identification of pancreatic cancer invasion-related proteins by proteomic analysis [PDF]
Background – Markers of pancreatic cancer invasion were investigated in two clonal populations of the cell line, MiaPaCa-2, Clone #3 (high invasion) and Clone #8 (low invasion) using proteomic profiling of an in vitro model of pancreatic cancer ...
Naomi Walsh +21 more
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BackgroundEx vivo liver resection and autotransplantation (ELRAT) may provide an opportunity for R0 resection of conventionally unresectable hepatobiliary cancers and hepatic metastases.
Shaoyan Xu +14 more
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Gemcitabine: Progress in the treatment of pancreatic cancer [PDF]
Unresectable pancreatic cancer has a dismal prognosis with a median survival of 3-5 months in untreated disease. Since the introduction of gemcitabine, pancreatic cancer may no longer be regarded a chemotherapy-resistant tumor.
Heinemann, Volker
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Pancreatic endocrine tumors [PDF]
The endocrine cells of the pancreas and their related cells throughout the gastrointestinal tract give rise to a variety of tumors that pose a diagnostic challenge. There has been progress in understanding their histogenesis, morphology, immunohistochemistry, molecular biology and classifications.
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Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer [PDF]
Tumor angiogenesis is a process that requires migration, proliferation, and differentiation of endothelial cells. We hypothesized that decrease in pancreatic tumor growth due to inhibition of src activity is associated with the inability of src kinase to
Ischenko, Ivan
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BackgroundHepatocellular cancer (HCC) is one of the most common tumors worldwide, and Ki-67 is highly important in the assessment of HCC. Our study aimed to evaluate the value of ultrasound radiomics based on intratumoral and peritumoral tissues in ...
Hongwei Qian +6 more
doaj +1 more source
A systematic pan-cancer analysis of PXDN as a potential target for clinical diagnosis and treatment
Peroxidasin (PXDN), also known as vascular peroxidase-1, is a newly discovered heme-containing peroxidase; it is involved in the formation of extracellular mesenchyme, and it catalyzes various substrate oxidation reactions in humans.
Xiaohu Zhou +14 more
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CUL4B, NEDD4, and UGT1As involve in the TGF-β signalling in hepatocellular carcinoma
Introduction and Aim. TGF-β signalling is involved in pathogenesis and progress of hepatocellular carcinoma (HCC). This bioinformatics study consequently aims to determine the underlying molecular mechanism of TGF-β activation in HCC cells.Material and ...
Zhaowei Qu +7 more
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In 1902, Nicholls described a tumor originating from a pancreatic islet cell lineage [1]. This was the first report of a pancreatic endocrine tumor (PET). These uncommon tumors occur in approximately 1 out of 100,000 people [2–4]. The incidence in autopsy studies is as high as 1.5% [5].
John C, Mansour, Herbert, Chen
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