Results 31 to 40 of about 552,612 (348)

Immune Checkpoint FGL1 Expression of Circulating Tumor Cells Is Associated With Poor Survival in Curatively Resected Hepatocellular Carcinoma

Frontiers in Oncology, 2022
LAG-3 is one of the common tumor immune checkpoints. LAG-3 can inhibit the activation and proliferation of T cells, and can also suppress immunity by regulating other immune-related cell functions.
Qing Yan, Qing Yan, Hao-Ming Lin, Ke Zhu, Yi Cao, Xiao-Lin Xu, Zi-Yu Zhou, Lei-bo Xu, Chao Liu, Rui Zhang   +9 more
doaj   +1 more source

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev, Ganeshan, Dhakshinamoorthy, Lubner, Meghan G., Menias, Christine O., Pickhardt, Perry J., Ramalingam, Preetha, Sandrasegaran, Kumaresan   +6 more
core   +1 more source

Skeletal muscle metastasis from extrahepatic cholangiocarcinoma: A case report and literature review

Frontiers in Surgery, 2022
BackgroundCholangiocarcinoma (CCA) is a type of malignant tumor that arises from the epithelium of the bile ducts. According to anatomical location, CCA can be classified as intrahepatic (ICC), perihilar (PCC), or extrahepatic (ECC).
Hongwei Qian, Hongwei Qian, Zhikun Huang, Zhikun Huang, Xuezheng Sun, Xuezheng Sun, Peitu Ren, Peitu Ren   +7 more
doaj   +1 more source

Differences in Clinical Features and Diagnostic Strategies Between IgG4-Related Autoimmune Cholangitis and Cholangiocarcinoma

Frontiers in Oncology, 2021
IgG4-related autoimmune cholangitis (IgG4-AIC) is often difficult to distinguish from cholangiocarcinoma (CCA). This study aimed to determine a practical clinical strategy for distinguishing between IgG4-AIC and CCA to avoid unnecessary surgical ...
Ke Zhu, Jin Yang, Ying-zhen Chen, Xue-rong Zhang, Xian-huan Yu, Jie Wang, Rui Zhang, Chao Liu   +7 more
doaj   +1 more source

Regulation of pancreatic cancer aggressiveness by stromal stiffening [PDF]

, 2016
No abstract ...
A Neesse, AD Rhim, BC Özdemir, H Laklai, I Barbieri, JJ Lee, JK Mouw, JM Bailey, Michael F Olson, Nicola Rath, P Bailey, SR Hingorani, SR Hingorani, V Sanz-Moreno   +13 more
core   +1 more source

Geriatric nutritional risk index and body composition dictate the prognosis of elderly patients with intrahepatic cholangiocarcinoma

Frontiers in Nutrition
Background and aimsMalnutrition is a well-recognized predictor of poor prognosis in malignancies. Recent studies suggest that the geriatric nutritional risk index (GNRI) is a more accurate determinant of prognosis in elderly patients than conventional ...
Sheng Wang, Luo Cheng, Lei Dou, Yuanli Kuang, Yang Huang, Tao Wen, Lei Xiang, Wenyuan Xie, Cheng Zhang, Dewei Li, Hui Li   +10 more
doaj   +1 more source

Cell-derived extracellular vesicles and membranes for tissue repair

Journal of Nanobiotechnology, 2021
Humans have a limited postinjury regenerative ability. Therefore, cell-derived biomaterials have long been utilized for tissue repair. Cells with multipotent differentiation potential, such as stem cells, have been administered to patients for the ...
Yuan Ding, Yanjie Li, Zhongquan Sun, Xin Han, Yining Chen, Yao Ge, Zhengwei Mao, Weilin Wang   +7 more
doaj   +1 more source

Immune-related signature identifies IL1R2 as an immunological and prognostic biomarker in pancreatic cancer

Journal of Pancreatology
Objective:. Pancreatic cancer is one of the most aggressive malignancies, a robust prognostic signature and novel biomarkers are urgently needed for accurate stratification of the patients and optimization of clinical decision-making. Methods:. A list of
Chengcheng Wang, Yuan Chen, Xinpeng Yin, Ruiyuan Xu, Rexiati Ruze, Jianlu Song, Chenglin Hu, Yupei Zhao   +7 more
doaj   +1 more source

Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression [PDF]

, 2017
Gastrointestinal cancer is a group of tumors that affect multiple sites of the digestive system, including the stomach, liver, colon and pancreas. These cancers are very aggressive and rapidly metastasize, thus identifying effective targets is crucial ...
Bacigalupo, Maria Lorena, Carabias, Pablo, Troncoso, María Fernanda   +2 more
core   +1 more source

A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells. [PDF]

, 2016
The MST1R gene is overexpressed in pancreatic cancer producing elevated levels of the RON tyrosine kinase receptor protein. While mutations in MST1R are rare, alternative splice variants have been previously reported in epithelial cancers.
Babicky, M, Chakedis, J, French, R, Holman, P, Howard, H, Jaquish, D, Lam, R, Lowy, AM, Miyamoto, J, Mose, E, Walterscheid, Z   +10 more
core   +2 more sources