3DGAUnet: 3D generative adversarial networks with a 3D U-Net based generator to achieve the accurate and effective synthesis of clinical tumor image data for pancreatic cancer [PDF]
Pancreatic ductal adenocarcinoma (PDAC) presents a critical global health challenge, and early detection is crucial for improving the 5-year survival rate. Recent medical imaging and computational algorithm advances offer potential solutions for early diagnosis.
arxiv +1 more source
MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells. [PDF]
Pancreatic adenocarcinoma is one of the most leading causes of cancer-related deaths worldwide. Although recent advances provide various treatment options, pancreatic adenocarcinoma has poor prognosis due to its late diagnosis and ineffective therapeutic
Chen, Qiu-Dan+8 more
core +2 more sources
Endocrine Pancreatic Tumors [PDF]
Neuroendocrine tumors of the pancreas are rare neoplasms that may arise sporadically or in association with a hereditary endocrine neoplasia syndrome. Effective management requires directed biochemical testing, careful choice of preoperative imaging tests, and complete pancreatic exploration by an experienced endocrine surgeon utilizing intraoperative
J. F. Moley, T. C. Lairmore
openaire +2 more sources
Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing worldwide. Sharing powerful genetic and environmental features in their pathogenesis, obesity amplifies the impact of genetic susceptibility and environmental factors ...
Rexiati Ruze+20 more
doaj +1 more source
Adrenomedullin in pancreatic carcinoma. a case-control study of 22 patients [PDF]
Pancreatic carcinoma is a leading cause of cancer-related death. Reduction of the diagnostic delay is mandatory. Adrenomedullin (AM) is overexpressed in pancreatic cancer.
ANTOLINO, LAURA+5 more
core +1 more source
Neutrophil in the Pancreatic Tumor Microenvironment [PDF]
Pancreatic ductal adenocarcinoma (PDAC) is a malignancy with a poor prognosis and low survival rates. PDAC is characterized by a fibroinflammatory tumor microenvironment enriched by abundant fibroblasts and a variety of immune cells, contributing to its aggressiveness.
Lin Jin, Hong Sun Kim, Jiaqi Shi
openaire +4 more sources
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen+3 more
wiley +1 more source
Background and aimsMalnutrition is a well-recognized predictor of poor prognosis in malignancies. Recent studies suggest that the geriatric nutritional risk index (GNRI) is a more accurate determinant of prognosis in elderly patients than conventional ...
Sheng Wang+10 more
doaj +1 more source
Background: Hepatitis B virus (HBV) infection is a major risk factor causing hepatocellular carcinoma (HCC) development, but the molecular mechanisms are not fully elucidated.
Wanyu Deng+17 more
doaj +1 more source
DeformableFormer: Classification of Endoscopic Ultrasound Guided Fine Needle Biopsy in Pancreatic Diseases [PDF]
Endoscopic Ultrasound-Fine Needle Aspiration (EUS-FNA) is used to examine pancreatic cancer. EUS-FNA is an examination using EUS to insert a thin needle into the tumor and collect pancreatic tissue fragments. Then collected pancreatic tissue fragments are then stained to classify whether they are pancreatic cancer.
arxiv