Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. [PDF]
, 2015 Chronic pancreatitis (CP) is a progressive and irreversible inflammatory and fibrotic disease with no cure. Unlike acute pancreatitis (AP), we find that alternatively activated macrophages (AAMs) are dominant in mouse and human CP.
Chawla, Ajay +6 more
core +2 more sources
Differential Diagnosis for Pancreatic Cysts in CT Scans Using Densely-Connected Convolutional Networks [PDF]
arXiv, 2018 The lethal nature of pancreatic ductal adenocarcinoma (PDAC) calls for early differential diagnosis of pancreatic cysts, which are identified in up to 16% of normal subjects, and some of which may develop into PDAC. Previous computer-aided developments have achieved certain accuracy for classification on segmented cystic lesions in CT.
arxiv
Hypertriglyceridemia and acute pancreatitis: clinical and basic research—a narrative review
Journal of PancreatologyHypertriglyceridemia (HTG) is the third most common cause of acute pancreatitis (AP), and the incidence of HTG-induced AP (HTG-AP) is rising worldwide as a result of changes in lifestyle and dietary habits.
Lin Gao, Weiqin Li
doaj +1 more source
Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model. [PDF]
, 2012 Pancreatic duct glands (PDGs) have been hypothesized to give rise to pancreatic intraepithelial neoplasia (PanIN). Treatment with the glucagon-like peptide (GLP)-1 analog, exendin-4, for 12 weeks induced the expansion of PDGs with mucinous metaplasia and
Butler, Peter C +5 more
core +1 more source
Gastroenterología y Hepatología, 2011 The present article summarizes some of the most important results with potential clinical impact on the diagnosis and management of chronic pancreatitis presented at the last meeting of Digestive Disease Week. Endoscopic ultrasound (EUS) is currently the method of choice for the diagnosis of chronic pancreatitis in clinical practice.
openaire +3 more sources
Src as the link between inflammation and cancer. [PDF]
, 2013 Although a causal link between chronic inflammation and cancer has been established, the exact molecular mechanism linking inflammation to cancer remains largely unknown.
Andrzej ePtasznik +4 more
core +2 more sources
Pancreatogenic type 3C diabetes [PDF]
, 2018 Background. The relationship between chronic pancreatitis and diabetes is well established. This form of diabetes is secondary to exocrine pancreatic disorder and is known as diabetes mellitus type 3c (T3cDM). Materials and Methods. In this retrospective
Diaconu, Camelia C +11 more
core +1 more source
Post-surgical Pancreatitis Masquerading as Recurrent Neuroendocrine Cancer [PDF]
, 2010 Neuroendocrine tumours of the pancreas can have a spectrum of behaviour from relatively benign to aggressive. Resection can result in cure although metastatic disease is described.
Adair, Anya +2 more
core +2 more sources
Optical detection of fractal dimensions of MUC13 stained pancreatic tissues for cancer diagnostics [PDF]
arXiv, 2018 Transmission intensity of a thin tissue sample produce intensity distribution that is proportional to the refractive index pattern in the thin slice, in turn reflects mass density pattern, and using the intensity pattern, fractal dimension can be calculated. In this paper, we report fractal dimension analyses of MUC13 stained pancreatic cancer tissues.
arxiv
Multifocal High-Grade Pancreatic Precursor Lesions: A Case Series and Management Recommendations [PDF]
, 2019 Background: The risk of developing invasive cancer in the remnant pancreas after resection of multifocal high-grade pancreatic precursor lesions is not well known.
Carr, Rosalie A. +5 more
core +1 more source