Results 71 to 80 of about 166,885 (311)

Network Toxicology and Molecular Docking Analysis of Tetracycline-Induced Acute Pancreatitis: Unveiling Core Mechanisms and Targets

Toxics
Acute pancreatitis (AP), induced by tetracycline, a widely used antibiotic, poses significant clinical and toxicological challenges, yet its molecular mechanisms remain unclear.
Hang Lei, Yimao Wu, Wenjun Ma, Jiaqi Yao, Pengcheng Zhang, Yong Tian, Yuhong Jiang, Zhijun Xie, Lv Zhu, Wenfu Tang   +9 more
doaj   +1 more source

Ileal Mucosal and Fecal Pancreatitis Associated Protein Levels Reflect Severity of Salmonella Inflection in Rats

, 2009
Background Microbial infections induce ileal pancreatitis-associated protein/regenerating gene III (PAP/RegIII) mRNA expression. Despite increasing interest, little is known about the PAP/RegIII protein.
van der Meer, R., Bovee-Oudenhoven, I.M.J., Ampting, M.T.J., van, Schonewille, A., Kramer, E., Keijer, J., Meer, R., van der, van Ampting, M.T.J., Rodenburg, G.C.H., Vink, C.   +9 more
core   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Klebsiella predominance in peripancreatic microbial spectrum is associated with the severity of infected pancreatic necrosis

BMC Infectious Diseases
Background Infectious pancreatic necrosis (IPN) is associated with the prognosis of acute pancreatitis (AP). The correlation between microbial diversity in the peripancreatic region and AP severity remains unclear.
Xiaolan Guo, Yao Xu, Kaiwei Li, Jingzhu Zhang, Zhihui Tong, Weiqin Li, Donghuang Hong   +6 more
doaj   +1 more source

Correlation between Protection against Sepsis by Probiotic Therapy and Stimulation of a Novel Bacterial Phylotype

, 2011
Item does not contain fulltextProphylactic probiotic therapy has shown beneficial effects in an experimental rat model for acute pancreatitis on the health status of the animals.
Smidt, H., Gooszen, H.G., Rijkers, G.T., Minnen, L.P. van, van Minnen, L.P., Fuentes, S., Akkermans, L.M., Hauke Smidt, Minnen, L.P., van, Frans M. Rombouts, Gerritsen, J., Ger T. Rijkers, Susana Fuentes, Jacoline Gerritsen, Konstantinov, S.R., Akkermans, L.M.A., Rombouts, F.M., Panneman, H., Harro M. Timmerman, Henk Panneman, Louis M. A. Akkermans, L. Paul van Minnen, Hein G. Gooszen, Timmerman, H.M., Sergey R. Konstantinov   +24 more
core   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Chronic pancreatitis

Southern Medical Journal, 1963
Chronic pancreatitis is caused most often by chronic excessive alcohol consumption. The disease can be diagnosed by investigations that measure function or assess morphology of the pancreas, thereby permitting a tailored management approach. In many patients, abdominal pain and steatorrhea can be managed effectively by enzyme supplementation, provided ...
openaire   +4 more sources

Optimal timing of cholecystectomy after necrotising biliary pancreatitis

, 2022
Objective Following an episode of acute biliary pancreatitis, cholecystectomy is advised to prevent recurrent biliary events. There is limited evidence regarding the optimal timing and safety of cholecystectomy in patients with necrotising biliary ...
Dutch Pancreatitis Study Group
core  

Coagulopathy and acute pancreatitis: pathophysiology and clinical treatment

Frontiers in Immunology
Coagulopathy is a critical pathophysiological mechanism of acute pancreatitis (AP), arising from the complex interplay between innate immune, endothelial cells and platelets.
Lan Li, Lan Li, Qingyuan Tan, Qingyuan Tan, Xueying Wu, Xiaowen Mou, Xiaowen Mou, Ziqi Lin, Tingting Liu, Wei Huang, Wei Huang, Lihui Deng, Tao Jin, Tao Jin, Qing Xia, Qing Xia   +15 more
doaj   +1 more source