Results 51 to 60 of about 254,687 (213)

Time-Course Lipidomics of Ornithine-Induced Severe Acute Pancreatitis Model Reveals the Free Fatty Acids Centered Lipids Dysregulation Characteristics

open access: yesMetabolites, 2023
The relationship between the type and intensities of lipids of blood and pancreas and the pathological changes in the pancreas during severe acute pancreatitis (SAP) remains unclear.
Jinxi Yang   +11 more
doaj   +1 more source

Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. [PDF]

open access: yes, 2015
Chronic pancreatitis (CP) is a progressive and irreversible inflammatory and fibrotic disease with no cure. Unlike acute pancreatitis (AP), we find that alternatively activated macrophages (AAMs) are dominant in mouse and human CP.
Chawla, Ajay   +6 more
core   +2 more sources

Pancreatitis and Pancreatic Cancer Risk

open access: yesTechnology in Cancer Research & Treatment, 2023
Purpose: The present retrospective study aimed to explore the relationship between pancreatitis and pancreatic cancer in the population cohort of the UK Biobank (UKB) ( https://www.ukbiobank.ac.uk ). Methods: From the 500 thousand population cohort of UKB, according to the age and gender of patients with pancreatic cancer 1:10, matching the control ...
Dong-Mei Ma   +6 more
openaire   +3 more sources

Annular pancreas: endoscopic and pancreatographic findings from a tertiary referral ERCP center [PDF]

open access: yes, 2019
Background and Aims Annular pancreas is a congenital anomaly whereby pancreatic tissue encircles the duodenum. Current knowledge of endoscopic findings of annular pancreas is limited to small case series.
Easler, Jeffrey J.   +10 more
core   +1 more source

Pancreatic Cancer in Chronic Pancreatitis [PDF]

open access: yesIndian Journal of Surgical Oncology, 2015
Data exists to indicate a definite association between chronic pancreatitis and pancreatic cancer. The strength of this association varies between various causes of pancreatitis, with hereditary and tropical pancreatitis more likely to result in malignancy. Pathogenesis may involve genetic factors, diabetes, smoking and alcohol consumption.
Puneet, Dhar, S, Kalghatgi, Vivek, Saraf
openaire   +2 more sources

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

open access: yesFrontiers in Physiology, 2019
Pancreatic acinar cells require high rates of amino acid uptake for digestive enzyme synthesis, but excessive concentrations can trigger acute pancreatitis (AP) by mechanisms that are not well understood.
Xiaoying Zhang   +17 more
doaj   +1 more source

Hemoconcentration is associated with early faster fluid rate and increased risk of persistent organ failure in acute pancreatitis patients

open access: yesJGH Open, 2020
Background Controversies existed surrounding the use of hematocrit to guide early fluid therapy in acute pancreatitis (AP). The association between hematocrit, early fluid therapy, and clinical outcomes in ward AP patients needs to be investigated ...
Tao Jin   +18 more
doaj   +1 more source

Infected Necrosis in Severe Pancreatitis - Combined Nonsurgical Multi-Drainage with Directed Transabdominal High-Volume Lavage in Critically Ill Patients [PDF]

open access: yes, 2009
Background: Infection of pancreatic necrosis is a life-threatening complication during the course of acute pancreatitis. In critically ill patients, surgical or extended endoscopic interventions are associated with high morbidity and mortality. Minimally
A. Meining   +31 more
core   +1 more source

Staging chronic pancreatitis with exocrine function tests: Are we better? [PDF]

open access: yes, 2017
Chronic pancreatitis (CP) is an inflammatory disease of the pancreas evolving in progressive fibrotic disruption of the gland with exocrine and endocrine pancreatic insufficiency.
MOLETTA, LUCIA, SPERTI, COSIMO
core   +1 more source

Role of Seipin in Human Diseases and Experimental Animal Models

open access: yesBiomolecules, 2022
Seipin, a protein encoded by the Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2) gene, is famous for its key role in the biogenesis of lipid droplets and type 2 congenital generalised lipodystrophy (CGL2). BSCL2 gene mutations result in genetic
Yuying Li   +7 more
doaj   +1 more source

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