Results 51 to 60 of about 183,025 (305)

Ileal Mucosal and Fecal Pancreatitis Associated Protein Levels Reflect Severity of Salmonella Inflection in Rats [PDF]

, 2009
Background Microbial infections induce ileal pancreatitis-associated protein/regenerating gene III (PAP/RegIII) mRNA expression. Despite increasing interest, little is known about the PAP/RegIII protein.
van der Meer, R., Bovee-Oudenhoven, I.M.J., Ampting, M.T.J., van, Schonewille, A., Kramer, E., Keijer, J., Meer, R., van der, van Ampting, M.T.J., Rodenburg, G.C.H., Vink, C.   +9 more
core   +1 more source

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

What should be measured and reported in clinical trials for the treatment of patients with acute pancreatitis? A study protocol for establishing a core outcome set

BMJ Open, 2023
Introduction Acute pancreatitis (AP) is characterised by inflammation of the exocrine pancreas, which potentially leads to local complications and organ failure resulting in significant morbidity and mortality.
Wei Huang, Ling Li, Xin Sun, Chen Hu, Lihui Deng, Ping Zhu, Qing Xia, Weiwei Chen, Yuxin Shen, Zhiyao Chen, Ziqi Lin, Qingyuan Tan   +11 more
doaj   +1 more source

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

Advanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu, Yiyin Rong, Bai Sun, Ziwen Sun, Yifan Wang, Xiaobin Ren, Zelin Cao, Kaikai Gao, Jiawei Yu, Zhenkun Wang, Haoxuan Ma, Jichun Guo, Kai Cao, Mengrun Kang, Songling Wang, Fenggang Ren, Yi Lv, Qiang Lu   +17 more
wiley   +1 more source

Impact of admission and early persistent stress hyperglycaemia on clinical outcomes in acute pancreatitis

Frontiers in Endocrinology, 2022
BackgroundTo determine the impact of glucose levels at admission and during first week (early phase) on clinical outcomes in patients with acute pancreatitis (AP) and to investigate the relationship between stress hyperglycaemia (SHG) and ...
Xinmin Yang, Na Shi, Linbo Yao, Wenhua He, Ping Zhu, Sheyu Li, Sheyu Li, Lan Li, Yuying Li, Shiyu Liu, Lihui Deng, Tao Jin, Tingting Liu, Nonghua Lu, John A. Windsor, Robert Sutton, Yin Zhu, Qing Xia, Wei Huang   +18 more
doaj   +1 more source

Pancreatic pseudocyst eroding into the splenoportal venous confluence and mimicking an arterial aneurysm [PDF]

, 2009
We report the case of a 62-year-old man with chronic pancreatitis who presented with increasing abdominal pain. Sonography, magnetic resonance imaging, contrast-enhanced computed tomography, and ultimately catheter angiography demonstrated a pancreatic ...
Naguib, Nagy N., Lehnert, Thomas, Vogl, Thomas J. (Prof. Dr.), Nour-Eldin A. Nour-Eldin, Thomas J. Vogl, Naguib, Nagy Naguib Naeem, Koitka, Karen, Nagy N. Naguib, Alhajii, Waleed, Thomas Lehnert, Mohammed, Nour-Eldin Abdelrehim Nour-Eldin, Nour-Eldin, Nour-Eldin A., Karen Koitka, Vogl, Thomas J., Waleed Alhajii   +14 more
core   +1 more source

Immunomagnetic‐MXene Bifunctional Probes for Ultrasensitive and Specific Terahertz Metasensing of Tumor‐Derived Exosomes

Advanced Science, EarlyView.
An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin, Jiyue Chen, Fengxin Xie, Huiyan Tian, Xuechen Dou, Yanqi Han, Lu Zhang, Jining Li, Xiang Yang   +8 more
wiley   +1 more source

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

Frontiers in Physiology, 2019
Pancreatic acinar cells require high rates of amino acid uptake for digestive enzyme synthesis, but excessive concentrations can trigger acute pancreatitis (AP) by mechanisms that are not well understood.
Xiaoying Zhang, Xiaoying Zhang, Tao Jin, Tao Jin, Na Shi, Linbo Yao, Xinmin Yang, Chenxia Han, Li Wen, Dan Du, Peter Szatmary, Rajarshi Mukherjee, Tingting Liu, Qing Xia, David N. Criddle, Wei Huang, Michael Chvanov, Robert Sutton   +17 more
doaj   +1 more source

Correlation between Protection against Sepsis by Probiotic Therapy and Stimulation of a Novel Bacterial Phylotype [PDF]

, 2011
Item does not contain fulltextProphylactic probiotic therapy has shown beneficial effects in an experimental rat model for acute pancreatitis on the health status of the animals.
Smidt, H., Gooszen, H.G., Rijkers, G.T., Minnen, L.P. van, van Minnen, L.P., Fuentes, S., Akkermans, L.M., Hauke Smidt, Minnen, L.P., van, Frans M. Rombouts, Gerritsen, J., Ger T. Rijkers, Susana Fuentes, Jacoline Gerritsen, Konstantinov, S.R., Akkermans, L.M.A., Rombouts, F.M., Panneman, H., Harro M. Timmerman, Henk Panneman, Louis M. A. Akkermans, L. Paul van Minnen, Hein G. Gooszen, Timmerman, H.M., Sergey R. Konstantinov   +24 more
core   +1 more source