Results 61 to 70 of about 166,885 (311)

Chronic pancreatitis and pancreatic carcinoma [PDF]

open access: yesPostgraduate Medical Journal, 1997
Summary The differential diagnosis between pancreatic cancer and chronic pancreatitis is very important as the management and prognosis of these two diseases is different. In most patients with pancreatic disease, the diagnosis can be established but there is a subgroup of patients in whom it is difficult to differentiate between these ...
J D, Evans   +2 more
openaire   +2 more sources

Longitudinal Phenotypic Trajectories in GNAO1‐Related Disorders: Defining Disease Progression and Clinical Profiles

open access: yesAnnals of Neurology, EarlyView.
Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral   +52 more
wiley   +1 more source

PANCREATIC LYMPHANGITIS AND CHRONIC PANCREATITIS [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1913
The most important subject which is occupying the attention of abdominal surgeons to-day has to do with the elucidation of the pathogenesis, the recognition of the symptoms and the discovery of adequate means of treatment of the diseases of the pancreas.
openaire   +2 more sources

Caracterització dels tipus d'activació de diferents poblacions de macròfags durant la pancreatitis aguda experimental i la seva relació amb la severitat del procés [PDF]

open access: yes, 2011
Malgrat els esforços dedicats a investigar la pancreatitis aguda (PA), segueixen sense resposta la major part de les preguntes plantejades fa anys. En particular, encara no es coneixen tots els mecanismes pels que una lesió localitzada en el pàncrees pot
Gea-Sorlí, Sabrina, Gea Sorli, Sabrina
core  

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola   +14 more
wiley   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić   +8 more
wiley   +1 more source

Clinical characteristics and prognosis of older adult patients with necrotizing pancreatitis: a single center retrospective study

open access: yesJournal of Pancreatology
Background:. Acute pancreatitis (AP) is a common condition encountered during clinical practice; 20% of patients have pancreatic necrosis, and the mortality is high.
Yue Wu, JiongDi Lu, Feng Cao, Fei Li
doaj   +1 more source

Identification of the nucleotide sequence of the lipoprotein lipase gene as well as its role in the development of hyperlipidemia and pancreatitis in the Miniature Schnauzer [PDF]

open access: yes, 2005
Lipoprotein Lipase (LPL) is a key enzyme in lipid transport. It catalyses the hydrolysis of the triacylglycerol component of chylomicrons and very low-density lipoproteins (VLDL), providing non-esterified fatty acids for tissue utilization.
Schickel, Ralph
core  

Pancreatic pseudocyst eroding into the splenoportal venous confluence and mimicking an arterial aneurysm

open access: yes, 2009
We report the case of a 62-year-old man with chronic pancreatitis who presented with increasing abdominal pain. Sonography, magnetic resonance imaging, contrast-enhanced computed tomography, and ultimately catheter angiography demonstrated a pancreatic ...
Naguib, Nagy N.   +14 more
core   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad   +4 more
wiley   +1 more source

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