Results 91 to 100 of about 128,122 (265)

Molecular Mechanisms and Therapeutic Potential of Baicalein in Acute Pancreatitis: A Comprehensive Review

Biomolecules
Acute pancreatitis (AP) is a severe inflammatory disorder characterized by a complex molecular pathophysiology involving premature zymogen activation, organelle dysfunction, and systemic immune dysregulation. Current therapeutic strategies remain largely
Linbo Yao, Shiyu Liu, Wei Huang, Xinmin Yang   +3 more
doaj   +1 more source

A real‐world analysis of AI chatbot performance for medicines information enquiries

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background The provision of medicines information (MI) services requires interpretation and clinical judgement of complex scenarios by pharmacists. To date, few studies have assessed the performance of artificial intelligence (AI) chatbots to assist pharmacists providing MI advice.
Duncan Yorkston, Tracey Borrie, Paul Chin   +2 more
wiley   +1 more source

Ocular facial myositis and sialadenitis presenting with new onset ulcerative colitis

JPGN Reports, EarlyView.
Abstract Extra‐intestinal manifestations of inflammatory bowel disease (IBD) can involve most organ systems, although the immunologic underpinnings are not well understood. Most patients who present with an extra‐intestinal manifestation have a single site of extra‐intestinal involvement; however, a small cohort presents with multiple different sites ...
Nicole Du, Nicole Mendez, Anil Darbari
wiley   +1 more source

Myeloid sarcoma presenting as an isolated pancreatic mass in a 3‐year‐old child

JPGN Reports, EarlyView.
Abstract Myeloid sarcoma (MS) is an extramedullary tumor of myeloid precursor cells, frequently associated with acute myeloid leukemia (AML), and rarely occurring in isolation. We present a child with obstructive jaundice secondary to a pancreatic head mass.
Jappmann Kaur Monga, Cara L. Mack, Michelle Saad, Dylan Applin, Maisam Abu‐El‐Haija, David Vitale, Zachary Graff, Gila Ginzburg   +7 more
wiley   +1 more source

Complementary and alternative medicine use by patients in pediatric gastroenterology clinics

JPGN Reports, EarlyView.
Abstract Objectives Use of complementary and alternative medicine (CAM) therapies among children seen in pediatric gastroenterology (GI) clinics is high. Multiple CAM therapies are effective as primary and adjuvant therapies for GI disorders and symptoms. Our study aimed to define the historical use of CAM and interest in CAM therapies in a specialized
Joshua D. Prozialeck, Lauren M. Potthoff, Bridget Whitehead, John E. Fortunato   +3 more
wiley   +1 more source

Nutrient-sensing alteration leads to age-associated distortion of intestinal stem cell differentiating direction

Nature Communications
Nutrient-sensing pathways undergo deregulation in aged animals, exerting a pivotal role in regulating the cell cycle and subsequent stem cell division.
Zihua Yu, Yuedan Zhu, Yi Chen, Chenxi Feng, Zehong Zhang, Xiaoxin Guo, Haiou Chen, Xingzhu Liu, Yu Yuan, Haiyang Chen   +9 more
doaj   +1 more source

[Pancreatitis].

Revista de la Facultad de Medicina, Universidad Nacional de Colombia, 1956
Se presenta en forma esquemática y sucinta el problema de las pancreatitis, con los conocimientos hasta hoy adquiridos sobre ellas, e incluyendo la Bibliografía correspondiente al año 55 y parte del 56. Bibliografía anterior puede consultarse en la obra fundamental de Catell y en el artículo de L. F. Bond y R. Elman.
openaire   +2 more sources

Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single‐centre Australian experience

JPGN Reports, EarlyView.
Abstract Objectives To evaluate the durability and predictors of loss of response of infliximab (IFX) over 2 years in paediatric Crohn's disease (CD) utilizing a proactive therapeutic drug monitoring (TDM) strategy. Methods A retrospective, single‐centre cohort study was conducted at The Children's Hospital at Westmead (CHW), Australia, from January ...
Cher Wei Chuah, Jessica Eldredge, Annabel Magoffin, Edward Vincent O'Loughlin, Calvin Joomann Park, Juliana Puppi, Susan Siew, Michael Stormon, Kunal Thacker, Shoma Dutt   +9 more
wiley   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Acute pancreatitis: mechanisms and therapeutic approaches

Signal Transduction and Targeted Therapy
Acute pancreatitis is a complex inflammatory condition characterized by sudden onset and rapid progression, with severe cases often associated with high mortality.
Qian Hu, Yue Hu, Chunlu Tan, Yue Yang, Hang Su, Zixing Huang, Wenfu Tang, Rui Wang, Jingping Liu, Meihua Wan   +9 more
doaj   +1 more source