Results 61 to 70 of about 1,254,937 (311)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The Effects of Tourism on the GDP of Macedonia, Montenegro and Serbia in the Process of European Integration

Amfiteatru Economic, 2016
Tourism is a socio-economic phenomenon exerting considerable economic, social and political impact, thus securing itself an important position in the overall economic growth.
Slobodan Čerović , Miroslav Knežević , Danijel Pavlović   +2 more
doaj  

Determinants of Profitability in the Banking Sector: An Analysis of Post-Soviet Countries

Economies, 2018
The purpose of this paper is to identify the determinants of bank profitability in 13 post-Soviet countries. Within this scope, annual data between 1996 and 2016 is analyzed by using fixed effects panel regression and the Generalized Method of Moments ...
Serhat Yüksel, Shahriyar Mukhtarov, Elvin Mammadov, Mustafa Özsarı   +3 more
doaj   +1 more source

Classification of nonparametric regression functions in heterogeneous panels [PDF]

SSRN Electronic Journal, 2015
We investigate a nonparametric panel model with heterogeneous regression functions. In a variety of applications, it is natural to impose a group structure on the regression curves. Specifically, we may suppose that the observed individuals can be grouped into a number of classes whose members all share the same regression function.
Michael Vogt, Oliver Linton
openaire   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Civil Service, HR Potential, and Open Innovation

Journal of Open Innovation: Technology, Market and Complexity, 2020
Countries strive to upgrade their civil service quality in many directions, thus responding to major contemporary challenges and following the trends of open innovation.
Aleksandra Polyakova
doaj   +1 more source

Panel regression models for measuring multidimensional poverty dynamics [PDF]

Statistical Methods & Applications, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
BETTI, GIANNI, DAGOSTINO A, NERI, LAURA
openaire   +4 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Modelling primary health care use: a panel zero inflated interval regression approach [PDF]

, 2012
We introduce the (panel) zero-inflated interval regression (ZIIR) model, to investigate GP visits using individual-level data from the British Household Panel Survey.
Brown, S., Harris, M.N., Roberts, J., Taylor, K.   +3 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source