Results 131 to 140 of about 1,556 (147)

Identifying crossovers in a cattle pangenome containing haplotype-resolved assemblies from half-siblings

Leonard AS, Pausch H.
europepmc   +1 more source

Pangenome graphs and their applications in biodiversity genomics [PDF]

Nature Genetics
Complete datasets of genetic variants are key to biodiversity genomic studies. Long-read sequencing technologies allow the routine assembly of highly contiguous, haplotype-resolved reference genomes. However, even when complete, reference genomes from a single individual may bias downstream analyses and fail to adequately represent genetic diversity ...
Guido Gallo, Simona Secomandi, Erich Jarvis   +2 more
exaly   +5 more sources

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Investigating Pangenome Graphs Using Wheat Panache

Methods in Molecular Biology, 2023
Pangenome graphs quickly become the central data structure representing the diversity of variation we see across related genomes. Pangenome graphs have been published for some species, including plants of agronomic interest. However, visualizing these graphs is not easy as the graphs are large, and variants within these graphs are complex.
, Philipp Emanuel Bayer, Bayer Philipp E
exaly   +3 more sources

From de Bruijn Graphs to Variation Graphs – Relationships Between Pangenome Models

Lecture Notes in Computer Science, 2023
Submitted to International Symposium on String Processing and Information Retrieval. Cham: Springer Nature Switzerland, 2023 (SPIRE2023). This preprint has not undergone peer review or any post-submission improvements or corrections. The Version of Record of this contribution is published in LNCS, volume 14240, and is available online at https://doi ...
Norbert Dojer, Adam Cicherski
exaly   +3 more sources

Are we there yet? Driving the road to evolutionary graph-pangenomics

Current Opinion in Plant Biology, 2022
With increase in the number of sequenced genomes, it is now recognized that graph-based pangenomes can provide a comprehensive platform to study diversity in a population or species, from point mutations to large chromosomal rearrangements. By incorporating concepts from graph theory, a graph-pangenome can be studied directly to identify genomic ...
openaire   +2 more sources

Personalizing pangenome graphs with k-mers

Nature Genetics
exaly   +3 more sources

Graph pangenomes find missing heritability

Nature Genetics, 2022
David Edwards, Jacqueline Batley
openaire   +2 more sources

From Genomics to Pangenomics: the path to pangenome graphs

2023
Gautreau, Guillaume, Bazin, Adelme, Arnoux, Jérôme   +2 more
openaire   +1 more source

A Pangenome Approach to Detect and Genotype TE Insertion Polymorphisms

Methods in Molecular Biology, 2022
Cristian Groza, Clement Goubert, Guillaume Bourque   +2 more
exaly  

Building pangenome graphs

Nature Methods
Santiago Marco-Sola, Andrea Guarracino, Joep De Ligt   +2 more
exaly