Results 21 to 30 of about 22,873 (246)

Human MuStem cells repress T-cell proliferation and cytotoxicity through both paracrine and contact-dependent pathways

open access: yesStem Cell Research & Therapy, 2022
Background Muscular dystrophies (MDs) are inherited diseases in which a dysregulation of the immune response exacerbates disease severity and are characterized by infiltration of various immune cell types leading to muscle inflammation, fiber necrosis ...
Marine Charrier   +19 more
doaj   +1 more source

Location and extent of unoccupied panther (Puma concolor coryi) habitat in Florida: Opportunities for recovery

open access: yesGlobal Ecology and Conservation, 2021
Breeding Florida panthers (Puma concolor coryi) are currently restricted to a small area in southwest Florida south of the Caloosahatchee River. Expansion of their range and numbers is necessary for long-term survival and recovery.
Robert A. Frakes, Marilyn L. Knight
doaj   +1 more source

Seasonal changes in network connectivity and consequences for pathogen transmission in a solitary carnivore

open access: yesScientific Reports, 2023
Seasonal variation in habitat use and animal behavior can alter host contact patterns with potential consequences for pathogen transmission dynamics.
Marie L. J. Gilbertson   +6 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Multiphoton microscopy and tissue clearing for 3D characterization of the vasculature and fibrosis remodeling in rat dystrophic skeletal muscle

open access: yesScientific Reports
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle fiber degeneration and replacement by fibrous and adipose tissues, alongside significant vascular abnormalities.
Ibrahim Hassani   +6 more
doaj   +1 more source

Integration of Low‐Voltage Nanoscale MoS2 Memristors on CMOS Microchips

open access: yesAdvanced Functional Materials, EarlyView.
This article presents the first monolithic integration of nanoscale MoS2‐based memristors into the back‐end‐of‐line of foundry‐fabricated CMOS microchips in a one‐transistor‐one‐resistor (1T1R) architecture. The MoS2‐based 1T1R cells exhibit forming‐free, nonvolatile resistive switching with ultra‐low operating voltages, low cycle‐to‐cycle variability ...
Jimin Lee   +16 more
wiley   +1 more source

The ancient egyptian roots of the image of the panther in the alexandrian Physiologus [PDF]

open access: yesВестник Православного Свято-Тихоновского гуманитарного университета: Сериа III. Филология, 2019
The purpose of this study is to trace the Old Egyptian roots of the Panther’s figure, symbolising the Saviour in the zoological mystery play Physiologus created in Egyptian Alexandria. Taking into account the opinion expressed in the literature about the
Eleonora Kormysheva
doaj   +1 more source

Sulfation‐Tunable Peptide‐Glycosaminoglycan Hydrogels for Hematopoietic Stem and Progenitor Cell Expansion

open access: yesAdvanced Functional Materials, EarlyView.
Co‐assembly of rationally designed glycosaminoglycan‐binding peptides with sulfated glycosaminoglycans yields supramolecular hydrogels with tunable mechanics and matrix‐mediated cytokine retention. The glycosaminoglycans thereby act as cofactors, driving a coil‐to‐β‐sheet transition that triggers gelation.
Shirel Veretnik   +8 more
wiley   +1 more source

Toward a Panther-centered View of the Forests of South Florida

open access: yesEcology and Society, 2000
Anthropogenic habitat degradation and loss is the single largest threat to the endangered Florida panther, Puma concolor coryi. Conservation of the subspecies must be undertaken on the scale of the entire landscape. Thus, a view of the forested landscape
Andrew J. Kerkhoff   +2 more
doaj   +1 more source

ASC nanobodies to counteract the consequences of inflammasome activation

open access: yesEMBO Molecular Medicine, 2022
Inflammasomes are multiprotein complexes that signal by oligomerizing the apoptosis speck‐like protein with caspase recruitment and activator domain (ASC) and are involved in multiple inflammatory, metabolic and degenerative diseases.
Sahil Adriouch, Pablo Pelegrin
doaj   +1 more source

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