Poly(N‐acryloyl glycine) hydrogel microparticles were fabricated via droplet‐based microfluidics and in situ photopolymerization. Rheology and MQ‐NMR revealed pronounced effects of pH and Ca2+ on network constraints and chain mobility, governing extensive swelling.
Yusuf Dursun +5 more
wiley +1 more source
ZNF865 (BLST) a Novel Regulator of DNA Damage and Cell Senescence in Back Pain
ZNF865 (BLST) has previously been classified as part of the “unknome”, but here in the context of back pain, we demonstrate the first functional characterization of ZNF865. We demonstrate that it regulates genomic stability and subsequent senescence, and that downregulation in the intervertebral disc leads to pain behavior in rodent models.
Christian Lewis +12 more
wiley +1 more source
Enzymatic Valorization of Whole Blue Crab (<i>Callinectes sapidus</i>) Biomass: Optimization of Proteolysis and Characterization of Protein Hydrolysates. [PDF]
Falciano A +3 more
europepmc +1 more source
Optimization of papain-assisted hydrolysis for salmon by-product protein powder production using response surface methodology. [PDF]
Rachapila T.
europepmc +1 more source
Continuous 28‐day light exposure alters behaviours of articular cartilage progenitor cells (ACPCs) and mesenchymal stromal cells (MSCs). Co‐culture with Leptolyngbya and Synechococcus does not adversely affect the chondrogenic capacity of ACPCs over a 28‐day period, in contrast to co‐culture with Chlorella.
Meng Wang +10 more
wiley +1 more source
Low-Molecular-Weight Salmon Collagen Peptides Promote Extracellular Matrix Gene (ECM) Expression in BJ Fibroblasts. [PDF]
Benjakul S +4 more
europepmc +1 more source
α‐Synuclein is a presynaptic protein extensively studied for its role in Parkinson's disease; however, its native function remains unclear. Here, we show that modest (approximately 2‐fold) overexpression of α‐synuclein in cultured neurons, at levels observed in familial synucleinopathies with SNCA triplication, impairs the endocytic retrieval of the ...
Elyas H. Arvell +7 more
wiley +1 more source
Various parts of <i>Carica</i> <i>papaya</i> L. - the cardioprotective potential and prospects for pharmacological use. [PDF]
Olas B.
europepmc +1 more source
Abstract Background Antibody identification testing is essential for preventing hemolytic transfusion reactions from unexpected red cell antibodies. Although automated interpretation is desirable to improve efficiency and consistency, conventional algorithmic approaches show limited accuracy, particularly in complex cases.
Jiwoo Lee +4 more
wiley +1 more source
From in silico screening to experimental verification: Identification of novel umami peptides from tamarind (<i>Tamarindus indica</i> L.) seed proteins and their validation in enzymatic hydrolysates. [PDF]
Huang S, Li S, Wang X, Jiu X, Cai S.
europepmc +1 more source

