Results 181 to 190 of about 63,884 (240)

Sigma‐1 Receptor‐Targeting Compounds Show Antiviral Activity Across Multiple Coronavirus Models

open access: yesJournal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Over the past two decades, coronaviruses have caused three major public health crises, including the epidemics of SARS‐CoV, MERS‐CoV, and SARS‐CoV‐2. Following the outbreak of SARS‐CoV‐2, several antiviral drugs have been approved for the treatment of COVID‐19.
Cuiling Zhang   +9 more
wiley   +1 more source

Evaluation of Probiotic Properties and Antimicrobial Substances Produced by Five Lactic Acid Bacteria Against Foodborne and Spoilage Pathogens

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
ABSTRACT The rise of multidrug‐resistant (MDR) pathogens presents a major challenge to food safety, particularly in preservation approaches. Lactic acid bacteria (LAB) gain probiotic recognition by effectively controlling MDR pathogens using antimicrobial substances (AMSs) and bacteriocin‐like inhibitory substances (BLISs).
Md. Moklesur Rahman   +5 more
wiley   +1 more source

A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis-like phenotype. [PDF]

open access: yesAnimal Model Exp Med
Yang H   +11 more
europepmc   +1 more source

Insights Into the Antibiofilm Activity of Carbon Quantum Dots Against a Panel of Different Microorganisms: A Review

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Carbon quantum dots (CDs) have emerged as versatile nanoplatforms for combating biofilm‐associated infections through multiple mechanisms, including EPS disruption, membrane damage, ROS generation, and quorum sensing inhibition. This review highlights how CD physicochemical properties and surface engineering strategies influence antibiofilm activity ...
Hadeer M. Bedair   +5 more
wiley   +1 more source

RheoScale 2.0: Revealing the hidden roles of protein positions via substitution patterns

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract A central challenge in molecular biology is understanding how amino acid substitutions modulate various features of protein function and stability. To illuminate the complexities of this relationship, high‐throughput (HTP) assays are increasingly used to assess site‐saturating mutagenesis libraries.
David H. Liu   +4 more
wiley   +1 more source

Coumarin‐Benzimidazole Hybrids as Multitarget Scaffolds for Antileishmanial Drug Discovery

open access: yesChemistrySelect, Volume 11, Issue 38, 13 October 2026.
Coumarin‐benzimidazole hybrids emerge as promising antileishmanial agents through virtual screening against essential Leishmania enzymes, Cathepsin B (CatB), and N‐myristoyltransferase (NMT). Molecular docking and dynamics simulations reveal highly stable target interactions that surpass the reference drug miltefosine (MTF).
Fernanda Melo Jucá   +4 more
wiley   +1 more source

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