Results 161 to 170 of about 63,884 (240)

Protease‐Triggered Chromogenic Release From Peptide‐Modified Calcium Carbonate Microspheres Enables Colorimetric Detection of Porphyromonas gingivalis Activity

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
We report a chromogenic release‐based assay system with protease‐cleavage peptide‐modified calcium carbonate microspheres for colorimetric detection of Porphyromonas (P.) gingivalis activity. In response to Arg‐specific gingipain secreted by P. gingivalis, the supernatant becomes colored, enabling colorimetric analysis and providing the monitoring of ...
Yuki Hiruta   +9 more
wiley   +1 more source

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

open access: yesAdvanced Science, Volume 13, Issue 60, 28 October 2026.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic   +21 more
wiley   +1 more source

Enzymatic Degradation of <i>Cryptosporidium</i> spp. Oocysts: A Combined In Silico and In Vitro Study. [PDF]

open access: yesMolecules
Souza DCT   +8 more
europepmc   +1 more source

ZBP1‐mediated Treg cell dysfunction exacerbates neuroimmune dysregulation in Alzheimer's disease under metabolic stress

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Metabolic stress increases Alzheimer's disease (AD) risk, but mechanisms linking metabolic dysfunction to neuroimmune dysregulation remain unclear. METHODS We assessed cognition in community‐dwelling participants and used high‐fat diet (HFD)‐fed 5xFAD mice, high glucose and high palmitate (HGHP)‐treated regulatory T cell (Treg) co‐
Shanshan Huang   +11 more
wiley   +1 more source

Seafood By‐Product Valorization: Emerging Extraction Technologies and Applications

open access: yesApplied Research, Volume 5, Issue 5, October 2026.
This review examines emerging extraction technologies for valorizing seafood by‐products and recovering high‐value compounds, including proteins, collagen, chitin, lipids, and bioactive peptides. It highlights their potential applications in food, health, and other industries, while discussing sustainability, industrial scalability, and research ...
Hasmadi Mamat   +8 more
wiley   +1 more source

Synthesis of 1,2,3‐Triazole Derivatives of N,N‐Dimethyltryptamine Isolated From Mimosa tenuiflora Root Bark: Antiplasmodial Activity In Silico and In Vitro

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
New 1,2,3‐disubstituted derivatives were synthesized from N,N‐dimethyltryptamine isolated from Mimosa tenuiflora and evaluated in vitro against chloroquine‐resistant P. falciparum W2. Compound 4 shows the best activity (IC50 = 4.8 ± µM) and selectivity index (> 10), while compound 7 shows the best binding energy (−9.8 kcal/mol) against PfPK7.
Renato Pinto de Sousa   +13 more
wiley   +1 more source

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