Results 101 to 110 of about 635,244 (311)
Development of Electrochemical and Colorimetric Biosensors for Detection of Dopamine
ChemosensorsNeurotransmitters are essential chemical messengers required for proper brain function, and any changes in their concentrations can lead to neuronal diseases. Therefore, sensitive and selective detection is crucial.
Rimsha Khan +7 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
, 2014 The advancement of sensor technology has led to an explosive increase in sensors. It causes semantic heterogeneity problems, and much research has focused on sensor ontology building to solve the problems.
이석훈, 김장원
core
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
A wireless sensor network based green marketplace for electrical appliances
, 2010 Wireless sensor and actuator networks are a promising tool to support energy monitoring and conservation. However, to date, research in this area has focused upon supporting infrastructure managers, while failing to consider the important role of ...
Kevin Lee +11 more
core +1 more source
Epidermal Passive RFID Strain Sensor for Assisted Technologies [PDF]
, 2014 An epidermal passive wireless strain sensor using RFID tags is presented. The tag is intended to detect eyebrow or neck skin stretch where paraplegic patients have the capability to tweak facial muscles.
Rumens, C.V. +3 more
core +1 more source
Graphene-Paper Based Electrochemical Sensors
, 2017 Graphene paper as a new form of graphene-supported nanomaterials has received worldwideattention since its first report in 2007. Due to their high flexibility, lightweight andgood electrical conductivity, graphene papers have demonstrated the promising potentialfor crucial applications in electrochemical sensors and energy technologies amongothers.
Zhang, Minwei +4 more
openaire +3 more sources