Results 81 to 90 of about 37,505,716 (291)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Sensitive and Discriminative Fluorescent Detection of Volatile Primary Aliphatic Diamine Vapors from Monoamines

open access: yesMolecules
The discriminative detection of volatile primary aliphatic diamines (VPADs) is a relevant and timely issue. This paper explores the distinctive optical features of H-type and J-type aggregates on paper-based (PB) films, namely H-PB and J-PB films ...
Agostino Attinà   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Hydrogen Sensing Using Paper Sensors with Pencil Marks Decorated with Palladium

open access: yesSensors, 2019
Paper-based sensors fabricated using the pencil-on-paper method are expected to find wide usage in many fields owing to their low cost and high reproducibility.
Nam Hee Lee   +2 more
doaj   +1 more source

Fibre Bragg grating based effective soil pressure sensor for geotechnical applications [PDF]

open access: yes, 2009
An effective-soil-pressure sensor for geotechnical applications based on Fibre Bragg Gratings is presented. The sensor simultaneous measures total soil pressure and pore pressure, allowing the calculation of the effective stress of soil.
Ricardo Correia   +17 more
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Topology control in Heterogeneous Wireless Sensor Network [PDF]

open access: yes, 2016
Topology of a Wireless Sensor Network determines the connectivity of the wireless network and topology Control is the important technique of extending network lifetime while preserving network connectivity.
Deshmukh, Prashant, Dandekar, Deepak R
core  

Ground reaction force sensor fault detection and recovery method based on virtual force sensor for walking biped robots [PDF]

open access: yes, 2013
This paper presents a novel method for ground force sensor faults detection and faulty signal reconstruction using Virtual force Sensor (VFS) for slow walking bipeds. The design structure of the VFS consists of two steps, the total ground reaction force (
Hashlamon, Iyad   +3 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Query management in a sensor environment [PDF]

open access: yes, 2008
Traditional sensor network deployments consisted of fixed infrastructures and were relatively small in size. More and more, we see the deployment of ad-hoc sensor networks with heterogeneous devices on a larger scale, posing new challenges for device ...
O\u27Connor, Martin F.   +6 more
core   +2 more sources

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