Results 61 to 70 of about 37,505,716 (291)

Highly Sensitive Water Detection Through Reversible Fluorescence Changes in a syn-Bimane Based Boronic Acid Derivative

open access: yesFrontiers in Chemistry, 2022
Reported herein is a fluorometric and colorimetric sensor for the presence of trace amounts of water in organic solvents, using syn-bimane based boronate ester 1. This sensor responds to the presence of water with a highly sensitive turn-off fluorescence
Apurba Pramanik   +3 more
doaj   +1 more source

Engineering Paper-Based Sensors for Zika Virus

open access: yesTrends in Molecular Medicine, 2016
The emergence of Zika virus (ZIKV) infections in Latin America and Southeast Asia has created an urgent need for new, simple, yet sensitive, diagnostic tests. We highlight recent work using paper-based sensors coupled with CRISPR/Cas9 to detect ZIKV RNA as a new approach to achieve rapid development and deployment of field-ready diagnostics for ...
Meagher, Robert J.   +2 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

User-friendly diameter-based measurement paper sensor for chloride detection in water

open access: yesTalanta Open
Chloride (Cl−) is an anion widely distributed in nature. It is also an essential parameter to consider when assessing the water quality for ensuring drinking water safety, preventing infrastructure damage, mitigating environmental impact, identifying ...
Benjarat Tasangtong   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Coordinated sleeping for beaconless 802.15.4-based multihop networks [PDF]

open access: yes, 2009
Paper presented at the 1st International Conference on Sensor Systems and Software, September 7-9, 2009 - Pisa, ItalyThe last few years have seen a wide adoption of the IEEE 802.15.4 MAC/PHY standard for low-power communication between wireless sensor ...
A. G. Ruzzelli   +9 more
core   +1 more source

Design and fabrication of paper-based stretchable sensor for respiration monitoring

open access: yes, 2021
Wearable electronics for health monitoring have recently been shown to provide significant benefits for early-stage disease identification. In this paper, we designed and fabricated a paper-based stretchable respiration sensor that utilizes graphite on ...
Nguyen, NT   +32 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Application of area-scan sensors in sensor-based sorting

open access: yes, 2018
S.73-82In the field of machine vision, sensor-based sorting is an important real-time application that enables the separation of a material feed into different classes.
Pfaff, F.   +10 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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