Results 71 to 80 of about 41,881,553 (292)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Cascading chemiresistive paper-based enzymatic biosensor for urea detection

Sensors and Actuators Reports
The conventional approach for diagnosing high risk metabolic disorders, such as chronic kidney disease (CKD), involves drawing a blood sample, which necessitates access to a centralized facility, making it undesirable for frequent urea monitoring ...
Ronil J. Rath, Jacopo Giaretta, Thanh Phuong Hoang, Riccardo Zulli, Syamak Farajikhah, Sepehr Talebian, Sina Naficy, Fariba Dehghani   +7 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Topology control in Heterogeneous Wireless Sensor Network [PDF]

, 2016
Topology of a Wireless Sensor Network determines the connectivity of the wireless network and topology Control is the important technique of extending network lifetime while preserving network connectivity.
Deshmukh, Prashant, Dandekar, Deepak R
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Metadata behind the Interoperability of Wireless Sensor Network [PDF]

, 2009
There is a current need not only to achieve, but also to maintain the interoperability of Wireless Sensor Networks despite frequent changes in network status. The aim of this paper is to describe a context-aware model for the interoperability of Wireless
Wachowicz, Monica, Daniela Ballari, Manso-Callejo, M.A., Wachowicz, M., Ballari, Daniela, Ballari, D.E., Manso Callejo, Miguel Ángel, Monica Wachowicz, Miguel Angel Manso Callejo   +8 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

PCDA–EDA Colorimetric Nanofiber Sensor for Rapid Visual GHB Screening: Linker Reassignment and Scalable Fabrication

Biosensors
γ-Hydroxybutyric acid (GHB), a colorless and odorless central nervous system depressant associated with drug-facilitated sexual assault, demands rapid on-site detection. Polydiacetylene (PDA) colorimetric sensors derived from 10,12-pentacosadiynoic acid (
Seunghye Yang, Jeongwook Lee, Om Darlami, Dongyun Shin   +3 more
doaj   +1 more source

Secure Clustering Protocols in Wireless Sensor Networks [PDF]

, 2016
Wireless sensor networks (WSNs) are poised of huge number of low-cost and tiny devices i.e. senor nodes which communicate over wireless media. Various WSN based projects produced fruitful and interesting results that greatly improves our life.
Sharma, S C, SINGH, SANTAR PAL
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source