Results 141 to 150 of about 93,899 (311)

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

What anesthesiologists should know about paracetamol (acetaminophen)

, 2009
Paracetamol is widely used in the management of acute and chronic pain. The purpose of this review is to give anesthesiologists answers to some of the most common questions about paracetamol, specifically the following questions. What is the mechanism of
COLUZZI, FLAMINIA, A. Mattia
core  

Overlay of ATR-FTIR spectra for identification: Pure paracetamol (red) and paracetamol tablet (blue).

, 2018
Overlay of ATR-FTIR spectra for identification: Pure paracetamol (red) and paracetamol tablet (blue).
Graham Lawson (5620934), Sangeeta Tanna (5620940), John Ogwu (5620937)   +2 more
core   +1 more source

Canine desexing attitudes and practices of Australian veterinarians: A cross‐sectional survey

Australian Veterinary Journal, EarlyView.
Canine desexing is one of the most common small animal surgical procedures in Australia, yet little is known about current practices. This study characterised attitudes, practitioner recommendations and surgical practices for routine canine desexing among Australian veterinarians using an online cross‐sectional survey (n = 107). Respondent demographics
S. Impey, M. Blevins, G. Chung, A. Goh, P. Rak   +4 more
wiley   +1 more source

A phase IIa study of the anti‐PD‐L1 antibody avelumab in relapsed/refractory PTCL: The AVAIL‐T trial

British Journal of Haematology, EarlyView.
The AVAIL‐T study, the first evaluation of programmed death ligand 1 (PD‐L1) blockade in relapsed/refractory peripheral T‐cell lymphomas (PTCL), demonstrated limited single agent activity with durable responses seen in a minority. Circulating tumour DNA revealed distinct mutational dynamics and mass cytometry identified perturbed T‐cell subsets ...
Matthew J. Ahearne, Matthew A. Timmins, Charlotte Gaskell, Aimee Jackson, Clare Morland, Sonia Fox, Louise Hopkins, Nadia Nawaz, Susann Lehmann, Marc Wadsley, Caroline Cowley, Jacqueline Shaw, Naeem Khan, Nagesh Kalakonda, Christopher Trethewey, Ram Malladi, Paul Fields, Dima El Sharkawi, Michael Quinn, Nimish Shah, Andrew Davies, Kim Linton, Pam McKay, Rod Johnson, Simon D. Wagner, David Lewis, Graham P. Collins, Christopher P. Fox, Kate Cwynarski   +28 more
wiley   +1 more source

Interaction between paracetamol and warfarin in patients: a double-blind, placebo-controlled, randomized study

Haematologica, 2006
BACKGROUND AND OBJECTIVES: Paracetamol (acetaminophen) has occasionally been reported to interact with warfarin. The primary end-point of this study was to investigate whether paracetamol initiation potentiates the anticoagulant effect of warfarin and ...
I Mahe, N Bertrand, L Drouet, C Bal Dit Sollier, G Simoneau, E Mazoyer, C Caulin, JF Bergmann   +7 more
doaj  

N of 1 trials comparing a non-steroidal anti-inflammatory drug with paracetamol in osteoarthritis

, 1994
Paracetamol appears to be as effective as diclofenac in alleviating pain associated with osteoarthritis when patients are given their choice of drug treatment. Paracetamol is also known as acetaminophen.
L March, March, L., Schwarz, J., Simpson, J., L Irwig, Brooks, P. M., J Schwarz, J Simpson, P Brooks, C Chock, Irwig, L., Chock, C.   +11 more
core   +1 more source

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

BJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui, Marlene Elmelund, Niels Klarskov   +2 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source