Results 51 to 60 of about 30,716 (258)

Molecular detection of Paracoccidioides in soil from an urban area of southern Brazil

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: Previous studies that detected Paracoccidioides spp. DNA in soil taken from rural areas have shown this to be a valuable tool for ecological and epidemiological studies. This study reports the detection of Paracoccidioides spp. DNA in soil
Josiara Furtado Mendes   +4 more
doaj   +1 more source

Proteomic Analysis of Paracoccidioides brasiliensis During Infection of Alveolar Macrophages Primed or Not by Interferon-Gamma

open access: yesFrontiers in Microbiology, 2019
Although members of the Paracoccidioides complex are not obligate intracellular pathogens, they present the ability to survive and multiply inside epithelial cells and phagocytes of mammals, which may favor the spread of the fungus in host tissues ...
Edilânia Gomes Araújo Chaves   +6 more
semanticscholar   +1 more source

Paracoccidioides Species Circulating in the Endemic Area of Rio de Janeiro, Brazil: Updates into Their Genetic Diversity

open access: yesJournal of Fungi
Paracoccidiodomycosis (PCM) is the most important systemic mycosis in Brazil, and is usually associated with rural work. PCM is caused by inhalation of infective propagules of thermodimorphic fungi from the genus Paracoccidioides.
Beatriz da Silva Motta   +6 more
doaj   +1 more source

Inquérito epidemiológico sobre a paracoccidioidomicose utilizando a gp43 em dois municípios do noroeste do Paraná, Brasil Paracoccidioidomycosis epidemiological survey using gp43, in two cities of northwestern region of Paraná, Brazil

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2005
Foi realizado um inquérito epidemiológico sobre paracoccidioidomicose com gp43, em 118 operários no Noroeste do Paraná. A positividade foi de 43%, o que aliado às condições ambientais favoráveis ao desenvolvimento do fungo reforçam que essa região seja ...
Nair Fornajeiro   +3 more
doaj   +1 more source

Extracellular vesicles from Paracoccidioides brasiliensis induced M1 polarization in vitro

open access: yesScientific Reports, 2016
Extracellular vesicles (EVs) released by eukaryotes, archaea, and bacteria contain proteins, lipids, polysaccharides, and other molecules. The cargo analysis of EVs shows that they contain virulence factors suggesting a role in the pathogenesis of ...
T. D. da Silva   +3 more
semanticscholar   +1 more source

Primers for Clinical Detection of Paracoccidioides brasiliensis [PDF]

open access: yesJournal of Clinical Microbiology, 2005
ABSTRACT From a 0.72-kb fragment universally generated in Paracoccidioides brasiliensis strains, primers were designed and tested on genomic DNA of this and other pathogenic fungi. They were specific and highly sensitive for P. brasiliensis DNA.
San-Blas, G.   +6 more
openaire   +4 more sources

Fungal DNA‐barcoding on a chip: Magnetoresistive biosensors for yeast infection diagnosis

open access: yesVIEW, EarlyView.
The development of a fungal pathogen identification chip is herein demonstrated. Hybridization dynamics were tested against 58 species in silico and 4 species on chip. 95% accuracy, 91% sensitivity, 98% specificity and femtomolar limit of detection were achieved. Future perspectives include the integration of sample pre‐treatment modules.
Maria Zolotareva   +8 more
wiley   +1 more source

Paracoccidioides spp.: the structural characterization of extracellular matrix, expression of glucan synthesis and associated genes and adhesins during biofilm formation

open access: yesFrontiers in Microbiology
The genus Paracoccidioides includes Paracoccidioides lutzii and the Paracoccidioides brasiliensis complex, which comprises four phylogenetic species. A key feature distinguishing planktonic growth from biofilm is the presence of a 3D extracellular matrix
Lariane Teodoro Oliveira   +7 more
doaj   +1 more source

NLRP3 Inflammasome Activation by Paracoccidioides brasiliensis

open access: yesPLoS Neglected Tropical Diseases, 2013
Paracoccidioides brasiliensis is the etiologic agent of paracoccidioidomycosis (PCM), the most prevalent systemic mycosis that is geographically confined to Latin America. The pro-inflammatory cytokine IL-1β that is mainly derived from the activation of the cytoplasmic multiprotein complex inflammasome is an essential host factor against opportunistic ...
Tavares, Aldo Henrique Fonseca Pacheco   +5 more
openaire   +5 more sources

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez   +3 more
wiley   +1 more source

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