Results 61 to 70 of about 30,716 (258)

Human serum antibody reactivity towards Paracoccidioides brasiliensis antigens treated with sodium metaperiodate Reatividade de anticorpos de soros humanos a antígenos de Paracoccidioides brasiliensis tratados com metaperiodato sódico

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2008
In this study, we evaluated the profile of anti-Paracoccidioides brasiliensis immunoglobulin isotypes in serum from patients with the acute and chronic forms of paracoccidioidomycosis, using the whole Paracoccidioides brasiliensis antigen and the antigen
Ana Paula Ferreira   +6 more
doaj   +1 more source

Molecular Phylogenetic Analysis of Paracoccidioides Species Complex Present in Paracoccidioidomycosis Patient Tissue Samples

open access: yesMicroorganisms, 2023
Paracoccidioidomycosis (PCM) is the main and most prevalent systemic mycosis in Latin America, that until recently, it was believed to be caused only by Paracoccidioides brasiliensis (P. brasiliensis). In 2006, researchers described three cryptic species:
Luciana Bonome Zeminian de Oliveira   +9 more
doaj   +1 more source

The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells

open access: yesFrontiers in Immunology, 2018
Plasmacytoid dendritic cells (pDCs), which have been extensively studied in the context of the immune response to viruses, have recently been implicated in host defense mechanisms against fungal infections.
N. Preite   +7 more
semanticscholar   +1 more source

THE POWER OF THE SMALL: THE EXAMPLE OF Paracoccidioides brasiliensis CONIDIA [PDF]

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2015
SUMMARYResearch on Paracoccidioides brasiliensis has centered in the yeast cell probably because of the lack of distinctive features in the mycelium. In 1942 and for the first time, lateral conidia were noticed in the fungus' hyphae. Later on, Brazilian, Venezuelan and Argentinean researchers described "aleurias" when the fungus was grown in natural ...
Restrepo Moreno, Ángela   +2 more
openaire   +7 more sources

Integrated In Silico – In Vitro Study Investigating Dipeptides as Chorismate Synthase Modulators: Spotlight on Its Mechanism of Action

open access: yesGlobal Challenges, Volume 9, Issue 12, December 2025.
This study integrates computational and experimental approaches to explore how short dipeptides modulate the activity of chorismate synthase. Unexpectedly, the GluAsp dipeptide enhanced enzyme activity by promoting a transient surface channel near the active site, possibly revealing a new structural feature relevant for microbial metabolism and ...
Lorenzo Pedroni   +4 more
wiley   +1 more source

Complexo primário da paracoccidioidomicose e hipereosinofilia Primary complex of paracoccidioidomycosis and hypereosinophilia

open access: yesJornal Brasileiro de Pneumologia, 2009
A infecção primária por Paracoccidioides brasiliensis é observada raramente. Um paciente masculino de 28 anos de idade apresentou febre, sintomas respiratórios e indisposição durante três meses. Exames radiológicos evidenciaram infiltrado pulmonar apical
Roberto Martinez, Maria Janete Moya
doaj   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

open access: yesImmunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder   +4 more
wiley   +1 more source

REACTIVITY OF ANTI-GP43 ANTIBODIES FROM PARACOCCIDIOIDES BRASILIENSIS ANTISERUM WITH EXTRACTS FROM CUTANEOUS LESIONS OF LOBO'S DISEASE: PRELIMINARY NOTE

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1997
We demonstrated through several immunochemical tests the presence of GP-43 from P. brasiliensis in extracts of cutaneous lesions from Jorge Lobo's disease.
Mônica Scarpelli Martinelli VIDAL   +3 more
doaj   +1 more source

Importance of xenarthrans in the eco-epidemiology of Paracoccidioides brasiliensis [PDF]

open access: yesBMC Research Notes, 2009
Several pathogens that cause important zoonotic diseases have been frequently associated with armadillos and other xenarthrans. This mammal group typically has evolved on the South American continent and many of its extant species are seriously threatened with extinction.
Richini-Pereira, Virgínia   +6 more
openaire   +5 more sources

Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses

open access: yesJournal of Extracellular Biology, Volume 4, Issue 8, August 2025.
ABSTRACT Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate interactions between fungal cells and hosts, significantly influencing the pathogen‐host relationship ...
Caroline P. de Rezende   +13 more
wiley   +1 more source

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