Results 111 to 120 of about 2,750 (239)

Hyperpolarization of [13C]formate using parahydrogen

Journal of Magnetic Resonance Open
Sodium [13C]formate was successfully hyperpolarized using parahydrogen-induced polarization by means of side-arm hydrogenation (PHIP-SAH). Allyl [13C]formate was hyperpolarized using homogeneous hydrogenation of the corresponding unsaturated precursor ...
Dudari B. Burueva, Sergey V. Sviyazov, Nikita V. Chukanov, Nazim R. Mustafin, Oleg G. Salnikov, Eduard Y. Chekmenev, Kirill V. Kovtunov, Igor V. Koptyug   +7 more
doaj   +1 more source

Continuous‐Wave (CW) Photo‐CIDNP NMR Spectroscopy: A Tutorial

Magnetic Resonance in Chemistry, Volume 63, Issue 12, Page 1020-1034, December 2025.
ABSTRACT Photo‐chemically induced dynamic nuclear polarisation (photo‐CIDNP) is a nuclear spin‐selective magnetic resonance phenomenon that has traditionally been used to mechanistically study chemical reactions involving the (transient) formation of radical molecular species, extract EPR observables of short‐lived radicals, probe biomolecular ...
Lars T. Kuhn, Míriam Pérez‐Trujillo
wiley   +1 more source

Optimal Variable Flip Angle Schemes for Hyperpolarized MR Kinetic Modeling Robust to RF Field Variations

NMR in Biomedicine, Volume 38, Issue 11, November 2025.
Optimization of variable flip angle schemes that minimize the variances of conversion rate estimates derived from hyperpolarized magnetic resonance experiments. Simulations based on in vitro experiments validated the improved parameter estimation and robustness of the optimized variable flip angle schemes.
Marie Frederikke Garnæs, Rie Beck Olin, Pernille R. Jensen, Jan Henrik Ardenkjaer‐Larsen, Kristoffer Hougaard Madsen, Lars G. Hanson   +5 more
wiley   +1 more source

Singlet to triplet conversion in molecular hydrogen and its role in parahydrogen induced polarization

, 2021
An analysis is reported of singlet-triplet conversion in molecular hydrogen dissolved in solution together with organometallic complexes used in experiments with parahydrogen (the H2 molecule in its nuclear singlet spin state).
Alexandra, Yurkovskaya, Danil, Markelov, Stephan , Knecht, Alexey , Kiryutin, Konstantin, Ivanov, Vitaly , Kozinenko   +5 more
core   +1 more source

Deep Learning for Hyperpolarized NMR of Intrinsically Disordered Proteins without Resolution Loss: Access to Short‐Lived Intermediates

Chemistry – A European Journal, Volume 31, Issue 59, October 22, 2025.
Abstract The inherently low sensitivity of solution‐state Nuclear Magnetic Resonance (NMR) has long limited its ability to characterize transient biomolecular states at atomic resolution. While dissolution dynamic nuclear polarization (dDNP) offers a compensating signal enhancement, its broader use has been hindered by rapid polarization decay, causing
Ertan Turhan, Christopher Pötzl, Dörte Brandis, Federico Faglia, Milan Zachrdla, Dennis Kurzbach   +5 more
wiley   +1 more source

Assessing a hyperpolarized [1-13C]-labeled alanine derivative enhanced via parahydrogen for in vivo studies

Journal of Magnetic Resonance Open
Magnetic Resonance Imaging (MRI) is a valuable non-invasive technique widely used in clinical diagnostics; however, its sensitivity is limited, posing challenges in various medical conditions.
Lisa M. Fries, Denis Moll, Ruhuai Mei, Theresa L․ K․ Hune, Josef Elsaßer, Stefan Glöggler   +5 more
doaj   +1 more source

The 13C hyperpolarized pyruvate generated by ParaHydrogen detects the response of the heart to altered metabolism in real time

Scientific Reports, 2018
Many imaging methods have been proposed to act as surrogate markers of organ damage, yet for many candidates the essential biomarkers characteristics of the injured organ have not yet been described.
E. Cavallari, Carla Carrera, Matteo Sorge, G. Bonne, A. Muchir, S. Aime, F. Reineri   +6 more
semanticscholar   +1 more source

Manipulating Stereoselectivity of Parahydrogen Addition to Acetylene to Unravel Interconversion of Ethylene Nuclear Spin Isomers

, 2023
Symmetric molecules exist as distinct nuclear spin isomers (NSIMs). A deeper understanding of their properties, including interconversion, requires efficient techniques for NSIMs enrichment.
Ivan V., Skovpin, Larisa M., Kovtunova, Dudari B., Burueva, Sergey V. , Sviyazov, Nikita V., Chukanov, Alexander Yu., Stakheev, Igor V., Koptyug, Simon V., Babenko   +7 more
core   +1 more source

Hyperpolarization with parahydrogen in NMR

, 2019
Parahydrogen based hyperpolarization can drastically boost NMR signals and merges many disciplines from science and technology. Especially, the relatively new SABRE approach is promising as it enables easy, affordable and repetitive hyperpolarization of ...
Lehmkuhl, Sören
core   +1 more source

Efficient Parahydrogen Induced 13C Hyperpolarization on a Microfluidic Device

We show the direct production and detection of 13C-hyperpolarized fumarate by parahydrogen-induced polarization (PHIP) in a microfluidic Lab-on-a-Chip (LoC) device and achieve 8.5% 13C polarization.
Marcel, Utz, Laurynas, Dagys, Malcolm, Levitt, Sylwia, Barker   +3 more
core   +1 more source