Results 71 to 80 of about 2,821 (200)

Low-cost High-Pressure Clinical-Scale 50% Parahydrogen Generator Using Liquid Nitrogen at 77 K

Analytical Chemistry, 2021
We report on a robust and low-cost parahydrogen generator design employing liquid nitrogen as coolant. The core of the generator consists of catalyst-filled spiral copper tubing, which can be pressurized to 35 atm. Parahydrogen fraction >48% was obtained
Benjamin J. Chapman, B. Joalland, Collier Meersman, J. Ettedgui, R. Swenson, M. Krishna, P. Nikolaou, K. Kovtunov, O. G. Salnikov, I. Koptyug, Max E. Gemeinhardt, B. Goodson, R. Shchepin, E. Chekmenev   +13 more
semanticscholar   +1 more source

Heterogeneous Parahydrogen Pairwise Addition to Cyclopropane [PDF]

ChemPhysChem, 2018
AbstractHyperpolarized gases revolutionize functional pulmonary imaging. Hyperpolarized propane is a promising emerging contrast agent for pulmonary MRI. Unlike hyperpolarized noble gases, proton‐hyperpolarized propane gas can be imaged using conventional MRI scanners with proton imaging capability.
Oleg G. Salnikov, Kirill V. Kovtunov, Panayiotis Nikolaou, Larisa M. Kovtunova, Valerii I. Bukhtiyarov, Igor V. Koptyug, Eduard Y. Chekmenev   +6 more
openaire   +2 more sources

Long nuclear spin coherence times for molecules trapped in high-purity solid parahydrogen

Physical Review Research
We measure the ensemble transverse relaxation time (T_{2}^{*}) and spin-echo coherence time (T_{2}) of the proton spin of HD molecules trapped in solid parahydrogen.
Alexandar P. Rollings, Jonathan D. Weinstein   +1 more
doaj   +1 more source

Minute‐Scale Repeated Metabolic Probing of Living Cells Enabled by Rapid Parahydrogen‐Based Hyperpolarization

Angewandte Chemie International Edition, EarlyView.
Rapid parahydrogen hyperpolarization combined with simple dilution enables biocompatible delivery of hyperpolarized pyruvate to immobilized living cells within ≈1 min. Repeated substrate injections reveal frequency‐dependent metabolic dynamics, introducing a new temporal dimension for hyperpolarized NMR studies of cellular metabolism and enabling rapid
Philipp R. Groß, Stefan Petersen, Zirun Wang, Behnam Shamshiri, Henri de Maissin, Sebastian Lucas, Oliver Gorka, Lisa Heß, Irene Marco‐Rius, Lluís Mangas‐Florencio, André F. Martins, Philipp Boehm‐Sturm, Maxim Zaitsev, Robert Zeiser, Jan‐Bernd Hövener, Thomas Reinheckel, Olaf Groß, Andreas B. Schmidt   +17 more
wiley   +1 more source

J Coupling Constants of <1 Hz Enable 13C Hyperpolarization of Pyruvate via Reversible Exchange of Parahydrogen

Journal of Physical Chemistry Letters
Observing pyruvate metabolism in vivo has become a focal point of molecular magnetic resonance imaging. Signal amplification by reversible exchange (SABRE) has recently emerged as a versatile hyperpolarization technique. Tuning of the spin order transfer
Charbel D Assaf, Xin Gui, Alexander A. Auer, S. Duckett, Jan‐Bernd Hövener, Andrey N. Pravdivtsev   +5 more
semanticscholar   +1 more source

Unveiling coherently driven hyperpolarization dynamics in signal amplification by reversible exchange

Nature Communications, 2019
There is increasing effort to improve the signal sensitivity and explore the hyperpolarization dynamics. Here the authors demonstrate the parahydrogen spin transfer dynamics in compounds containing 15N using SABRE hyperpolarization technique with ...
Jacob R. Lindale, Shannon L. Eriksson, Christian P. N. Tanner, Zijian Zhou, Johannes F. P. Colell, Guannan Zhang, Junu Bae, Eduard Y. Chekmenev, Thomas Theis, Warren S. Warren   +9 more
doaj   +1 more source

Nuclear‐Spin Hyperpolarization of Biomolecules by Optically Enhanced NMR at Ultra‐High Field

Journal of the Chinese Chemical Society, EarlyView.
This study shows that the sensitivity of liquid‐state NMR spectroscopy can be dramatically increased, with enhancement factors up to 160‐fold on a 1.1 GHz ultra‐high‐field NMR spectrometer. This advance exploits low‐concentration photochemically induced dynamic nuclear polarization (LC‐photo‐CIDNP) and it enables facile atomic‐resolution detection of ...
Ji Ho Jeong, Anubhab Halder, Silvia Cavagnero   +2 more
wiley   +1 more source

Efficient 15N hyperpolarization of [15N3]metronidazole antibiotic via spin-relayed pulsed SABRE-SHEATH

Journal of Magnetic Resonance Open
Signal Amplification by Reversible Exchange in SHield Enables Alignment Transfer to Heteronuclei (SABRE-SHEATH) is an NMR hyperpolarization technique that relies of the simultaneous exchange of parahydrogen and a to-be-hyperpolarized molecule on the ...
Shiraz Nantogma, Shannon L. Eriksson, Thomas Theis, Warren S. Warren, Boyd M. Goodson, Eduard Y. Chekmenev   +5 more
doaj   +1 more source

A Modified Balanced Steady State Free Precession Sequence for Overhauser Magnetic Resonance Imaging

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1655-1665, October 2026.
ABSTRACT Purpose Low‐ and ultralow‐field magnetic resonance imaging (ULF MRI) have inherently low signal‐to‐noise ratio (SNR) by design. Overhauser dynamic nuclear polarization (ODNP) stands out as an effective solution for continuous signal enhancement.
Kai Buckenmaier, Friedemann Bullinger, Georgiy Alekseevich Solomakha, Marcel Schneider, Jörn Engelmann, Philipp Pohlmann, Pavel Povolni, Laura Kuebler, André Ferreira Martins, Klaus Scheffler   +9 more
wiley   +1 more source

Uncertainty analysis of Raman spectra for measuring ortho-parahydrogen compositions

IOP Conference Series: Materials Science and Engineering
Determining ortho-parahydrogen compositions at cryogenic temperatures is an important quality control for liquid hydrogen custody exchange. High orthohydrogen compositions lead to an exothermic reaction resulting in increased boil off and increased ...
K. Appel, J. Leachman
semanticscholar   +1 more source