Results 81 to 90 of about 2,821 (200)

Ortho-parahydrogen catalyst test facility

IOP Conference Series: Materials Science and Engineering
With the growing interest in hydrogen as one pillar of the future energy economy, the relevance of hydrogen liquefaction for storage and transportation is increasing rapidly.
S. Eisenhut, C. Haberstroh
semanticscholar   +1 more source

Diazirines Beyond Photoaffinity Labeling: A Comprehensive Overview of Applications in Biological Sciences, Materials Chemistry, and NMR‐Spectroscopy

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Diazirines are three‐membered, nitrogen‐containing heterocycles that decompose under light or heat to generate carbenes. For the past two decades, they have served mainly as minimally invasive tags in photoaffinity labeling (PAL). More recently, their value as versatile carbene precursors has been recognized.
Dominik Schnalzer, Viktor Savic, Clemens Cziegler, Michael Schnürch, Marko D. Mihovilovic   +4 more
wiley   +2 more sources

Perpetual hyperpolarization of allyl acetate from parahydrogen and continuous flow heterogeneous hydrogenation with recycling of unreacted propargyl acetate

Journal of Magnetic Resonance Open, 2022
A novel closed loop, continuous flow (CF) reactor system for parahydrogen enhanced nuclear magnetic resonance (NMR) of liquids via heterogeneous catalysis is introduced which enables recycling of unreacted liquid substrate reactant.
Tommy Yunpu Zhao, Michelle P. Lapak, Ranjan Behera, Hanqin Zhao, Maria-Jose Ferrer, Helena E. Hagelin Weaver, Wenyu Huang, Clifford R. Bowers   +7 more
doaj   +1 more source

Real-Time Metabolic Magnetic Resonance Spectroscopy of Pancreatic and Colon Cancer Tumor-Xenografts with Parahydrogen Hyperpolarized 1-13C Pyruvate-d3.

Chemistry
Parahydrogen-induced polarization (PHIP) is an emerging technique to enhance the signal of stable isotope metabolic contrast agents for Magnetic Resonance (MR).
Lisa M. Fries, T. Hune, Sonja Sternkopf, Salvatore Mamone, Kim Lucia Schneider, Ramona Schulz-Heddergott, Dorothea Becker, S. Glöggler   +7 more
semanticscholar   +1 more source

Advancing homogeneous catalysis for parahydrogen-derived hyperpolarisation and its NMR applications

Chemical Science, 2022
Parahydrogen-induced polarisation (PHIP) is a nuclear spin hyperpolarisation technique employed to enhance NMR signals for a wide range of molecules. This is achieved by exploiting the chemical reactions of parahydrogen (para-H2), the spin-0 isomer of H2.
Ben. J. Tickner, V. Zhivonitko
semanticscholar   +1 more source

Parahydrogen-induced polarization allows 2000-fold signal enhancement in biologically active derivatives of the peptide-based drug octreotide

Scientific Reports, 2023
Octreotide, a somatostatin analogue, has shown its efficacy for the diagnostics and treatment of various types of cancer, i.e., in octreotide scan, as radio-marker after labelling with a radiopharmaceutical.
Jonas Lins, Yuliya A. Miloslavina, Stefania C. Carrara, Lorenz Rösler, Sarah Hofmann, Kevin Herr, Franziska Theiß, Laura Wienands, Olga Avrutina, Harald Kolmar, Gerd Buntkowsky   +10 more
doaj   +1 more source

Adiabatic Passage through Level Anticrossings in Systems of Chemically Inequivalent Protons Incorporating Parahydrogen: Theory, Experiment, and Prospective Applications

Journal of the American Chemical Society, 2022
Level anticrossings (LACs) are ubiquitous in quantum systems and have been exploited for spin-order transfer in hyperpolarized nuclear magnetic resonance spectroscopy. This paper examines the manifestations of adiabatic passage through a specific type of
M. Ferrer, Erin L Kuker, E. Semenova, Anghelo J Gangano, Michelle P. Lapak, Alexander J. Grenning, V. Dong, C. Bowers   +7 more
semanticscholar   +1 more source

A disintegrin derivative as a case study for PHIP labeling of disulfide bridged biomolecules

Scientific Reports, 2022
A specific labeling strategy for bioactive molecules is presented for eptifibatide (integrilin) an antiplatelet aggregation inhibitor, which derives from the disintegrin protein barbourin in the venom of certain rattlesnakes. By specifically labeling the
Max Fleckenstein, Kevin Herr, Franziska Theiß, Stephan Knecht, Laura Wienands, Martin Brodrecht, Michael Reggelin, Gerd Buntkowsky   +7 more
doaj   +1 more source

13C MRI of hyperpolarized pyruvate at 120 µT

Scientific Reports
Nuclear spin hyperpolarization increases the sensitivity of magnetic resonance dramatically, enabling many new applications, including real-time metabolic imaging.
Nicolas Kempf, Rainer Körber, Markus Plaumann, Andrey N. Pravdivtsev, Jörn Engelmann, Johannes Boldt, Klaus Scheffler, Thomas Theis, Kai Buckenmaier   +8 more
doaj   +1 more source

New para‐hydrogen cold neutron source at the Budapest Research Reactor: Monte Carlo simulations

Journal of Applied Crystallography, Volume 59, Issue 2, Page 392-403, April 2026.
This paper explores the options for upgrading the cold neutron source at the Budapest Research Reactor.The planned upgrade of the neutron guide system at the Budapest Research Reactor (BRR) provides an opportunity to enhance the performance of its cold neutron source.
Dmitrii Shapiro, Petr Konik, Mina Akhyani, Alexander Ioffe   +3 more
wiley   +1 more source