Results 61 to 70 of about 1,022,620 (339)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Expander $\ell_0$-Decoding [PDF]

open access: yes, 2015
We introduce two new algorithms, Serial-$\ell_0$ and Parallel-$\ell_0$ for solving a large underdetermined linear system of equations $y = Ax \in \mathbb{R}^m$ when it is known that $x \in \mathbb{R}^n$ has at most $k < m$ nonzero entries and that $A$ is
Mendoza-Smith, Rodrigo, Tanner, Jared
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Cover Edge-Based Novel Triangle Counting

open access: yesAlgorithms
Counting and listing triangles in graphs is a fundamental task in network analysis, supporting applications such as community detection, clustering coefficient computation, k-truss decomposition, and triangle centrality.
David A. Bader   +10 more
doaj   +1 more source

An adaptive enhancement method based on stochastic parallel gradient descent of glioma image

open access: yesIET Image Processing, 2023
Brain tumour diagnosis is significant for both physicians and patients, but the low contrast and the artefacts of MRI glioma images always affect the diagnostic accuracy.
Hongfei Wang   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Notes on Number Theory

open access: yesMathematics
This paper presents a set of survey-style notes linking core themes of pure algebra with central topics in algebraic and analytic number theory. We begin with finite extensions of Q and describe algebraic number fields through their realization as finite-
Miroslav Stoenchev   +2 more
doaj   +1 more source

MapReduce-Based Parallel Algorithms for Multidimensionnal Data Analysis

open access: yesJournal of Algorithms & Computational Technology, 2012
MapReduce has excellent scalability and fault-tolerance mechanism. It fits well with the cheap commodity hardware. Today, using MapReduce to answer data analytical query is an attractive topic.
Jie Pan   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

High-speed detection of emergent market clustering via an unsupervised parallel genetic algorithm

open access: yesSouth African Journal of Science, 2016
We implement a master-slave parallel genetic algorithm with a bespoke log-likelihood fitness function to identify emergent clusters within price evolutions.
Dieter Hendricks   +2 more
doaj   +1 more source

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