Results 101 to 110 of about 4,712,450 (295)

Enabling Detailed, Biophysics-Based Skeletal Muscle Models on HPC Systems

open access: yesFrontiers in Physiology, 2018
Realistic simulations of detailed, biophysics-based, multi-scale models often require very high resolution and, thus, large-scale compute facilities.
Chris P. Bradley   +22 more
doaj   +1 more source

Parallel Methods for Systems of Nonlinear Equations Applied to Load Flow Analysis [PDF]

open access: yes, 2013
A thesis submitted to the university of London in fulfillment of the requirements for the degree of Doctor of ...
Joubert, Adriaan
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

A Survey of Galaxy Pairs in the SDSS Photometric Images based on Faster-RCNN

open access: yesThe Astronomical Journal
Galaxy pairs hold significant importance in understanding the evolution of galaxies, and the extensive search for a large sample of galaxy pairs is meaningful.
Chen-hui Shi   +7 more
doaj   +1 more source

The PROOF Distributed Parallel Analysis Framework based on ROOT

open access: yes, 2003
The development of the Parallel ROOT Facility, PROOF, enables a physicist to analyze and understand much larger data sets on a shorter time scale. It makes use of the inherent parallelism in event data and implements an architecture that optimizes I/O ...
Ballintijn, Maarten   +3 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

A Sample of Am and Ap Candidates from LAMOST DR10 (v1.0) Based on the Ensemble Regression Model

open access: yesThe Astrophysical Journal Supplement Series
Large samples of Am and Ap stars are helpful in studying the interplay between phenomena like atomic diffusion, magnetic fields, and stellar rotation in stellar astrophysics.
Hai-Feng Yang   +10 more
doaj   +1 more source

Extraction Protocol for Parallel Analysis of Proteins and DNA from Ancient Teeth and Dental Calculus. [PDF]

open access: yesJ Proteome Res, 2023
Chocholova E   +6 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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