Results 121 to 130 of about 1,134,922 (335)

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Parallel Computing

open access: yes, 2023
AbstractThe concept of parallelism of computations is very important to obtain the results required by the algorithms of big data processing applied in several domains, like ML, AI, neural networks, approximate computing, etc. In this chapter the use of and stations and of their respective generation/synchronization policies are described [12]. Three
openaire   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Multitask Vehicle Signal Recognition With Dual-Speed Adaptive Weighting

open access: yesJournal of Advanced Transportation
In mixed traffic environments, the accurate identification of vehicular devices’ modulation schemes, communication protocols, and emitter device information directly affects perception capabilities toward surrounding vehicles and infrastructure. However,
Dianjing Cheng   +4 more
doaj   +1 more source

3DMeshNet: A three-dimensional differential neural network for structured mesh generation

open access: yesGraphical Models
Mesh generation is a crucial step in numerical simulations, significantly impacting simulation accuracy and efficiency. However, generating meshes remains time-consuming and requires expensive computational resources.
Jiaming Peng, Xinhai Chen, Jie Liu
doaj   +1 more source

A parallel variable metric optimization algorithm [PDF]

open access: yes
An algorithm, designed to exploit the parallel computing or vector streaming (pipeline) capabilities of computers is presented. When p is the degree of parallelism, then one cycle of the parallel variable metric algorithm is defined as follows: first ...
Straeter, T. A.
core   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Home - About - Disclaimer - Privacy