Results 81 to 90 of about 5,818,471 (412)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Workflow migration in uncertain edge computing environments based on interval many-objective evolutionary algorithm

open access: yesEgyptian Informatics Journal, 2023
In edge computing (EC), when the edge server (ES) is processing tasks delivered by the mobile devices (MDs), the MDs move outside the coverage of the ES, where task migration is required to ensure service continuity.
Zhenyu Shi   +4 more
doaj  

A Case for Security-Aware Design-Space Exploration of Embedded Systems

open access: yesJournal of Low Power Electronics and Applications, 2020
As modern embedded systems are becoming more and more ubiquitous and interconnected, they attract a world-wide attention of attackers and the security aspect is more important than ever during the design of those systems.
Andy D. Pimentel
doaj   +1 more source

Fractal Parallel Computing

open access: yesIntelligent Computing, 2022
As machine learning (ML) becomes the prominent technology for many emerging problems, dedicated ML computers are being developed at a variety of scales, from clouds to edge devices.
Yongwei Zhao, Yunji Chen, Zhiwei Xu
doaj   +1 more source

Efficient Ranking and Selection in Parallel Computing Environments [PDF]

open access: yesOperational Research, 2015
The goal of ranking and selection (R&S) procedures is to identify the best stochastic system from among a finite set of competing alternatives.
Eric Cao Ni   +3 more
semanticscholar   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Systematic Analysis of Low-Precision Training in Deep Neural Networks: Factors Influencing Matrix Computations

open access: yesApplied Sciences
As Deep Neural Networks (DNNs) continue to increase in complexity, the computational demands of their training have become a significant bottleneck. Low-precision training has emerged as a crucial strategy, wherein full-precision values are quantized to ...
Ao Shen, Zhiquan Lai, Lizhi Zhang
doaj   +1 more source

Overview and Applications of GPGPU Based Parallel Ant Colony Optimization [PDF]

open access: yesarXiv, 2022
Ant Colony Optimization algorithm is a magnificent heuristics technique based on the behavior of ants. Parallel computing is a means to achieve the desired results in commensurable execution time. Parallelization of Ant Colony Optimization is utilized to solve large and complex problems.
arxiv  

FFT for the APE Parallel Computer [PDF]

open access: yesInternational Journal of Modern Physics C, 1997
We present a parallel FFT algorithm for SIMD systems following the "Transpose Algorithm" approach. The method is based on the assignment of the data field onto a one-dimensional ring of systolic cells. The systolic array can be universally mapped onto any parallel system.
LIPPERT T   +4 more
openaire   +6 more sources

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

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