Results 251 to 260 of about 11,846 (303)

From Uncertainty to Pathogenicity: Resolving a CSF1R Variant of Uncertain Significance Using Long‐Read Transcriptomics

open access: yesMovement Disorders, EarlyView.
Abstract Background CSF1R‐related disorder (CSF1R‐RD) is a severe autosomal dominant leukoencephalopathy characterized by progressive cognitive, neuropsychiatric, and motor decline. Although genetic testing is widely available, numerous likely pathogenic variants in CSF1R frequently remain classified as variants of uncertain significance (VUS ...
Charles Wade   +8 more
wiley   +1 more source

Substitution urethroplasty for posterior urethral stenosis. [PDF]

open access: yesTransl Androl Urol
Kaldany A, Cedars B, Nikolavsky D.
europepmc   +1 more source

AI‐Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) is transforming synthetic chemistry from task‐specific predictors into integrated platforms that unify retrosynthesis, reaction optimization, and closed‐loop robotic automation. This review highlights how AI‐assisted planning and robotic execution shorten cycle times, reduce step counts, and improve route ...
Amit Gangwal, Antonio Lavecchia
wiley   +1 more source

The Human Penile Fibro-Vascular Assembly Requires the Integrity of Ten Fibro-Ligaments. [PDF]

open access: yesLife (Basel)
Chen HS   +7 more
europepmc   +1 more source

Semantic Embeddings of Chemical Elements for Enhanced Materials Inference and Discovery

open access: yesMaterials Genome Engineering Advances, EarlyView.
ElementBERT extracts semantic embeddings of chemical elements from 1.29 million alloy‐related abstracts, providing robust descriptors that improve prediction accuracy by up to 23% across titanium, high‐entropy, and shape memory alloys, with demonstrated generalization on alloy compositions reported in 2025.
Yunze Jia   +7 more
wiley   +1 more source

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