Results 61 to 70 of about 2,273,334 (347)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Kinematic and Dynamic Analysis of the Partially Decoupled Parallel Manipulator
Jixie chuandong, 2022 Aiming at the machining of complex curved surface parts with parallel machine tools， a novel partially decoupled parallel manipulator （PM） is proposed. The degree of freedom and the decoupling performance of the mechanism are analyzed.
Canguo Zhang +3 more
doaj
Parallel Manipulators with Lower Mobility [PDF]
, 2006 Parallel manipulators with lower mobility (LM-PMs) are multi-loop mechanisms with less than six degrees of freedom (dofs). This type of manipulators has attracted the attention both of academic researchers and of industries since the early appearance of the DELTA robot (Clavel 1988). The DELTA robot showed that, when the manipulation task requires less
openaire +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A study of the singularity locus in the joint space of planar parallel manipulators: special focus on cusps and nodes [PDF]
, 2011 Cusps and nodes on plane sections of the singularity locus in the joint space of parallel manipulators play an important role in nonsingular assembly-mode changing motions.
Chablat, Damien +2 more
core +2 more sources
Design and Analysis of an Annular 3-PPR Planar Parallel Mechanism
Jixie chuandong, 2023 In order to enlarge the rotation workspace of the manipulator, an annular 3-PPR planar parallel mechanism with full rotation capability is proposed. Resorting to homogeneous transformation and closed vector method, the inverse kinematics solution of the ...
Wu Xiaoyong, Li Yiyi, Zhang Kaifei
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Kinematic and Dynamic Analysis of the 2-DOF Spherical Wrist of Orthoglide 5-axis [PDF]
, 2009 This paper deals with the kinematics and dynamics of a two degree of freedom spherical manipulator, the wrist of Orthoglide 5-axis. The latter is a parallel kinematics machine composed of two manipulators: i) the Orthoglide 3-axis; a three-dof ...
Caro, Stéphane +3 more
core +2 more sources
Nonsingular change of assembly mode without any cusp [PDF]
, 2014 International audienceThis paper shows for the first time a parallel manipulator that can execute nonsingular changes of assembly modes while its joint space is free of cusp points and cuspidal edges.
C Innocenti +4 more
core +4 more sources