Results 61 to 70 of about 2,520,496 (344)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Kinematic and Dynamic Analysis of the Partially Decoupled Parallel Manipulator
Jixie chuandong, 2022 Aiming at the machining of complex curved surface parts with parallel machine tools， a novel partially decoupled parallel manipulator （PM） is proposed. The degree of freedom and the decoupling performance of the mechanism are analyzed.
Canguo Zhang +3 more
doaj
Parallel Manipulators with Lower Mobility [PDF]
, 2006 Parallel manipulators with lower mobility (LM-PMs) are multi-loop mechanisms with less than six degrees of freedom (dofs). This type of manipulators has attracted the attention both of academic researchers and of industries since the early appearance of the DELTA robot (Clavel 1988). The DELTA robot showed that, when the manipulation task requires less
openaire +3 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Design and Analysis of an Annular 3-PPR Planar Parallel Mechanism
Jixie chuandong, 2023 In order to enlarge the rotation workspace of the manipulator, an annular 3-PPR planar parallel mechanism with full rotation capability is proposed. Resorting to homogeneous transformation and closed vector method, the inverse kinematics solution of the ...
Wu Xiaoyong, Li Yiyi, Zhang Kaifei
doaj
Kinematic and Elastostatic Design Optimisation of the 3-DOF Gantry-Tau Parallel Kinematic Manipulator [PDF]
Modeling, Identification and Control, 2009 One of the main advantages of the Gantry-Tau machine is a large accessible workspace/footprint ratio compared to many other parallel machines. The Gantry-Tau improves this ration further by allowing a change of assembly mode without internal link ...
Ilya Tyapin, Geir Hovland
doaj +1 more source
A study of the singularity locus in the joint space of planar parallel manipulators: special focus on cusps and nodes [PDF]
, 2011 Cusps and nodes on plane sections of the singularity locus in the joint space of parallel manipulators play an important role in nonsingular assembly-mode changing motions.
Chablat, Damien +2 more
core +2 more sources
Optimal mapping of joint faults into healthy joint velocity space for fault-tolerant redundant manipulators [PDF]
, 2011 redundant ...
Abdi +12 more
core +3 more sources