Results 71 to 80 of about 2,273,334 (347)

Mechanism design and parameter optimization of a new asymmetric translational parallel manipulator [PDF]

Mechanical Sciences, 2019
With the requirement of heavy load for pick-and-place operation, a new 3-DoF asymmetric translational parallel manipulator is invented in this paper. This manipulator is assembled by a kinematic limb with the parallel linear motion elements(PLMEs), and a
Y. Yang, Y. Tang, H. Chen, Y. Peng, H. Pu   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

An Algorithm for Computing Cusp Points in the Joint Space of 3-RPR Parallel Manipulators [PDF]

, 2006
This paper presents an algorithm for detecting and computing the cusp points in the joint space of 3-RPR planar parallel manipulators. In manipulator kinematics, cusp points are special points, which appear on the singular curves of the manipulators. The
Chablat, Damien, Wenger, Philippe, Zein, Mazen   +2 more
core   +2 more sources

Identification of geometrical and elastostatic parameters of heavy industrial robots [PDF]

, 2013
The paper focuses on the stiffness modeling of heavy industrial robots with gravity compensators. The main attention is paid to the identification of geometrical and elastostatic parameters and calibration accuracy.
Caro, Stéphane, Dumas, Claire, Furet, Benoît, Klimchik, Alexandr, Pashkevich, Anatol, Wu, Yier   +5 more
core   +4 more sources

Mechanism Design and Simulation Analysis of Hybrid Serial-Parallel Underwater Dredging Manipulator

水下无人系统学报
In recent years, underwater robots have emerged as a novel solution for the removal of sediments at the bottom of reservoirs, with underwater manipulators being the primary tool for dredging operations.
Yin XIA, Wenbin SU, Qiao HU, Jian ZHANG, Lin SHI   +4 more
doaj   +1 more source

Computation of parallel link manipulator dynamics

Proceedings of IECON '93 - 19th Annual Conference of IEEE Industrial Electronics, 1994
This paper proposes an algorithm, for calculating the inverse dynamics of link manipulators. First, we derive a method to calculate the inverse dynamics of a general type of parallel link mechanism using the method proposed by Luh and Zeng., which is developed for a simple closed link mechanism and yields the inverse dynamics of the simple closed link ...
Kazuhiro Kosuge, Kouji Takeo, Toshio Fukuda, Katsumi Kai, Tomo Mizuno, Hiroaki Tomimatsu   +5 more
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Analysis and Design for 3-RPRR Similarly Planar Fully Compliant Parallel Manipulator

Jixie chuandong, 2015
A fully compliant parallel manipulator can achieve multi-dimensional motions,but it has obvious limitations in the micro-position fields for the structure and size.A new mechanism which is called 3-RPRR similarly planar fully compliant parallel ...
Zhu Dachang, Li Yan, Zhang Tao
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dynamic simulation of task constrained of a rigid-flexible manipulator

, 2004
A rigid-flexible manipulator may be assigned tasks in a moving environment where the winds or vibrations affect the position and/or orientation of surface of operation.
Ata, Atef A., Johar, Habib
core   +2 more sources