Kinematics analysis and design of 4PC-2R parallel mechanism
Xibei Gongye Daxue XuebaoWith the rapid development of new energy vehicle industry, the energy supply efficiency of a heavy electric truck becomes a key factor that restricts its wide application.
LUAN Fei +5 more
doaj +1 more source
Development of 6 DOF Displacement Sensor Using RUS Parallel Mechanism. [PDF]
Sensors (Basel), 2021 Kim D, Choi S, Yun D.
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Shanghai Jiaotong Daxue xuebaoIn order to isolate multi-dimensional vibration experienced by vehicle-mounted precise instrument, a novel multi-dimensional vibration isolator is proposed based on 2-RPC/2-SPC parallel mechanism and the magneto-rheological (MR) damper. The kinematic and
GAO Xiang, NIU Junchuan, HE Lei, QIN Zhen, WANG Zhonglong
doaj +1 more source
Study on the Algorithm of Multifunctional Bone External Fixator
MATEC Web of Conferences, 2015 This paper discussed the problem that parameters of bone external fixator are difficult to calculate in the practical application. Positive solution is described in detail. We used MATLAB software to make simulation experiment.
Chen Jianwen +3 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Forward and Inverse Dynamics of a Six-Axis Accelerometer Based on a Parallel Mechanism. [PDF]
Sensors (Basel), 2021 Wang L +5 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
From equilibrium models to mechanism design: On the place and the role of government in the public goods provision analysis in the second part of the twentieth century [PDF]
Focussing on their analysis of the optimal public goods provision problem, this paper follows the parallel development of equilibrium models and mechanism design after the accommodation of Samuelson's definition of collective goods to the general ...
Monique Florenzano
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source