Results 81 to 90 of about 492,436 (341)

NMDA Antagonist Peptide Supplementation Enhances Pain Alleviation by Adrenal Medullary Transplants

Cell Transplantation, 2005
Spinal transplantation of adrenal medullary chromaffin cells has been shown to decrease pain responses in several animal models. Improved potency may be possible by engineering cells to produce greater levels of naturally derived analgesics.
Farinaz Nasirinezhad, Jacqueline Sagen Ph.D.   +1 more
doaj   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Feasibility Study on Inflammasome Proteins as Biomarkers in the Cerebrospinal Fluid of Pediatric Patients with Hydrocephalus Due to Intraventricular Hemorrhage

Biomolecules
Pediatric hydrocephalus results from the overproduction, obstruction, or inability to resorb cerebrospinal fluid (CSF), which may lead to ventricular enlargement. Hydrocephalus may be secondary to other pathologies, including intraventricular hemorrhage (
MaryLourdes Andreu, Alexandra Castellanos, Robert W. Keane, Juan Pablo de Rivero Vaccari, Jennifer C. Muñoz Pareja, Helen M. Bramlett, W. Dalton Dietrich, Nadine A. Kerr, Heather J. McCrea   +8 more
doaj   +1 more source

Physiotherapy in the treatment of infantile paralysis

South African Journal of Physiotherapy, 1949
No abstract available.
E. Eeg
doaj   +1 more source

Declaraciones de Deseo y Declaraciones de Realidad : State-Indigenous Relations and Intercultural-Bilingual Education in Peru and Guatemala [PDF]

, 2011
Ethnic diversity has historically created conflict in many nation-states throughout the globe. From the era of nation-state formation to the present, states have had various strategies for dealing with this diversity. These strategies can be divided into
Christie, Emily
core   +1 more source

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

Article Commentary: Transplants of Neuronal Cells Bioengineered to Synthesize GABA Alleviate Chronic Neuropathic Pain

Cell Transplantation, 1999
The use of cell lines utilized as biologic “minipumps” to provide antinociceptive molecules, such as GABA, in animal models of pain is a newly developing area in transplantation biology.
M. J. Eaton Ph.D., J. A. Plunkett, M. A. Martinez, T. Lopez, S. Karmally, P. Cejas, S. R. Whittemore   +6 more
doaj   +1 more source

The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury

Journal of Neuroinflammation, 2019
Background Traumatic brain injury remains a significant cause of death and disability in the USA. Currently, there are no effective therapies to mitigate disability except for surgical interventions necessitating a need for continued research into ...
Stephanie W. Lee, Juan Pablo de Rivero Vaccari, Jessie S. Truettner, W. Dalton Dietrich, Robert W. Keane   +4 more
doaj   +1 more source

The role of the medical social worker in a polio epidemic: A study of fifty-eight cases referred to the Social Service Department of Haynes Memorial Hospital September and October, 1949 [PDF]

, 1950
Thesis (M.S.)--Boston ...
Haynes Memorial Hospital, Perry, Rose Louise   +1 more
core   +1 more source

Monoclonal gammopathy of clinical significance with Cervical spondylotic myelopathy presenting as severe paralysis: a case report [PDF]

, 2023
Junhu Li, Lei Wang, Yuemin Song
openalex   +1 more source