Results 91 to 100 of about 281,357 (305)

PERIODIC PARALYSIS [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1920
n ...
Guillain, G., Barré, J. A.
openaire   +1 more source

Molecular and phylogenetic characterization of honey bee viruses, Nosema microsporidia, protozoan parasites, and parasitic mites in China [PDF]

open access: yes, 2013
China has the largest number of managed honey bee colonies, which produce the highest quantity of honey and royal jelly in the world; however, the presence of honey bee pathogens and parasites has never been rigorously identified in Chinese apiaries.
Li, Tianbang   +7 more
core   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv   +16 more
wiley   +1 more source

Inhibition of microglia priming by NLRP3 reduces the impact of early life stress and mild TBI

open access: yesJournal of Neuroinflammation
Although most patients with mild traumatic brain injury (mTBI) experience rapid recovery, some report persistent chronic symptoms such as cognitive dysfunction. One risk factor for prolonged recovery after mTBI is early life stress (ELS). We hypothesized
Fabiola Placeres-Uray   +3 more
doaj   +1 more source

The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury

open access: yesJournal of Neuroinflammation, 2019
Background Traumatic brain injury remains a significant cause of death and disability in the USA. Currently, there are no effective therapies to mitigate disability except for surgical interventions necessitating a need for continued research into ...
Stephanie W. Lee   +4 more
doaj   +1 more source

Hysteric Paralysis [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1921
n ...
openaire   +2 more sources

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

open access: yesAdvanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou   +11 more
wiley   +1 more source

Targeted siRNA delivery reduces nitric oxide mediated cell death after spinal cord injury

open access: yesJournal of Nanobiotechnology, 2017
Background Traumatic spinal cord injury (SCI) includes the primary insult as well as a sequela of biochemical and cellular cascades that amplifies the initial injury.
Wen Gao, Jianming Li
doaj   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang   +12 more
wiley   +1 more source

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