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Paralytic Shellfish Toxins (PST)-Transforming Enzymes: A Review [PDF]

open access: yesToxins, 2020
Paralytic shellfish toxins (PSTs) are a group of toxins that cause paralytic shellfish poisoning through blockage of voltage-gated sodium channels.
Maria João Botelho   +2 more
exaly   +6 more sources

First Report of Paralytic Shellfish Toxins in Marine Invertebrates and Fish in Spain [PDF]

open access: yesToxins, 2020
A paralytic shellfish poisoning (PSP) episode developed in summer 2018 in the Rías Baixas (Galicia, NW Spain). The outbreak was associated with an unprecedentedly intense and long-lasting harmful algal bloom (HAB) (~one month) caused by the ...
Begoña Ben-Gigirey   +2 more
exaly   +4 more sources

A Sub-Acute Dosing Study of Saxitoxin and Tetrodotoxin Mixtures in Mice Suggests That the Current Paralytic Shellfish Toxin Regulatory Limit Is Fit for Purpose [PDF]

open access: yesToxins, 2023
Paralytic shellfish poisoning is a worldwide problem induced by shellfish contaminated with paralytic shellfish toxins. To protect human health, a regulatory limit for these toxins in shellfish flesh has been adopted by many countries. In a recent study,
Sarah C. Finch   +7 more
doaj   +3 more sources

An Occurrence and Exposure Assessment of Paralytic Shellfish Toxins from Shellfish in Zhejiang Province, China

open access: yesToxins, 2023
The intake of paralytic shellfish toxins (PSTs) may adversely affect human health. Therefore, this study aimed to show the prevalence of PSTs from commercially available shellfish in Zhejiang Province, China, during the period of frequent red tides ...
Dong Zhao
exaly   +3 more sources

Marine Biotoxins in Whole and Processed Scallops from the Argentine Sea

open access: yesMarine Drugs, 2022
Harmful algal blooms are an increasing worldwide threat to the seafood industry and human health as a consequence of the natural production of biotoxins that can accumulate in shellfish.
Alejandra B. Goya   +8 more
doaj   +1 more source

A Year of Bio-Monitoring (2021): Presence of Algae of the Genus Alexandrium, Dinophysis, Prorocentrum and Non-Compliance for Paralytic Toxins and Lipophilic Toxins in Bivalve Mollusks Bred in Sardinia (W Mediterranean Sea)

open access: yesJournal of Marine Science and Engineering, 2022
Bivalve mollusk production represents the principal aquaculture activity in Sardinia (40°03′ N, 9°05′ E). In 2021, 859 water samples and 1270 mollusk samples were analyzed.
Giuseppa Lorenzoni   +14 more
doaj   +1 more source

Biocatalytic Detoxification of Paralytic Shellfish Toxins [PDF]

open access: yesACS Chemical Biology, 2019
Small molecules that bind to voltage-gated sodium channels (VGSCs) are promising leads in the treatment of numerous neurodegenerative diseases and pain. Nature is a highly skilled medicinal chemist in this regard, designing potent VGSC ligands capable of binding to and blocking the channel, thereby offering compounds of potential therapeutic interest ...
April L. Lukowski   +5 more
openaire   +2 more sources

Substrate Promiscuity of a Paralytic Shellfish Toxin Amidinotransferase [PDF]

open access: yesACS Chemical Biology, 2020
Secondary metabolites are assembled by enzymes that often perform reactions with high selectivity and specificity. Many of these enzymes also tolerate variations in substrate structure, exhibiting promiscuity that enables various applications of a given biocatalyst.
April L. Lukowski   +7 more
openaire   +2 more sources

Shellfish Toxin Uptake and Depuration in Multiple Atlantic Canadian Molluscan Species: Application to Selection of Sentinel Species in Monitoring Programs

open access: yesToxins, 2021
Shellfish toxin monitoring programs often use mussels as the sentinel species to represent risk in other bivalve shellfish species. Studies have examined accumulation and depuration rates in various species, but little information is available to compare
Wade A. Rourke   +3 more
doaj   +1 more source

Immunoassay Methods for Paralytic Shellfish Poisoning Toxins [PDF]

open access: yesJournal of AOAC INTERNATIONAL, 2001
Abstract The current status of immunochemical techniques for analysis of paralytic shellfish poisoning (PSP) toxins is summarized. Important aspects regarding production of the biological reagents necessary for immunochemical methods, the characteristics of polyclonal and monoclonal antibodies against saxitoxin and neosaxitoxin, and the ...
E, Usleber   +4 more
openaire   +2 more sources

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